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Vol. 94. Issue 9.
Pages 441-444 (September 2019)
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Vol. 94. Issue 9.
Pages 441-444 (September 2019)
Short communication
Compressive optic neuropathy secondary to an allergic reaction to hyaluronidase
Neuropatía óptica compresiva secundaria a reacción alérgica a hialuronidasa
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R. Alcubierrea,b,
Corresponding author
, B.F. Sanchez-Dalmaua,c, K. Mousavia
a Centre Ocular Quirúrgic de Sant Boi, Sant Boi de Llobregat, Barcelona, Spain
b Departamento de Oftalmología, Hospital General de l’Hospitalet, Hospitalet de Llobregat, Barcelona, Spain
c Departamento de Oftalmología, Hospital Clínic, Barcelona, Spain
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Abstract

A 58 year-old woman presented with severe chemosis and ophthalmoparesis on her left eye 8h after uncomplicated cataract surgery under sub-tenon anaesthesia. Recovery of extrinsic motility was observed after corticosteroid and antihistamine treatment, but a non-haemorrhagic papillary oedema and a concentric defect of visual field were found. It progressed to papillary atrophy with preserved central vision, but with a significant visual field constriction. The aetiological study revealed an allergy to hyaluronidase that was used as adjuvant to the anaesthesia. This complication needs to be promptly diagnosed and treated, as the swelling of the orbital tissues can cause damage to the optic nerve.

Keywords:
Compressive optic neuropathy
Allergic reaction
Hyaluronidase
Resumen

Una mujer de 58años presentó quemosis intensa y oftalmoparesia en el ojo izquierdo 8h después de cirugía de catarata no complicada bajo anestesia subtenoniana. Tras tratamiento corticoideo y antihistamínico, se observó recuperación de la motilidad extrínseca pero se apreciaron un edema de papila no hemorrágico y un defecto concéntrico de campo visual. El caso evolucionó a atrofia papilar con agudeza visual central preservada pero con una contracción significativa del campo visual. El estudio etiológico reveló una alergia a la hialuronidasa, usada como adyuvante a la anestesia. Esta complicación debe ser diagnosticada y tratada precozmente, puesto que el edema de los tejidos orbitarios puede dañar el nervio óptico.

Palabras clave:
Neuropatía óptica compresiva
Reacción alérgica
Hialuronidasa

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