Background and aim: Obesity and diabetes 2 are health problems in western countries. And Mexico is probably the main cause of chronic liver disease. To assess the relationship of obesity and DM 2 as risk for chronic liver disease.
Material and methods: 200 patients with a diagnosis of chronic liver disease for 5 years in Gastroenterology were evaluated. 177 with a diagnosis of chronic liver disease. With support: ultrasound, fibroScan, biopsy, endoscopy; HbA1c, BH, PFH INR, ALBUMINE,), (HVC, HVB, AML, AMA, ANA and Ant-LKM-1 antibodies); Quantitative PCR; BMI.
Results: Patients with steatohepatitis and cirrhosis secondary to obesity and DM 68%, alcohol liver disease 14%, VHB and VHC liver disease 13%, autoimmune hepatitis 4%. The average age in steatohepatitis was 53.5 and in cirrhosis 63.4 years. The metabolic syndrome appeared in 47% of the patients with obesity and diabetes; the mean obesity was BMI> 35. The average glycated hemoglobin was 7.9% in patients with steatohepatitis and in patients with cirrhosis it was 7.6%. Cirrhosis secondary to obesity and diabetes accounted for 50% of all causes of cirrhosis in this study; steatohepatitis was also the leading cause of chronic liver damage.
Conclusions: Obesity and diabetes represent the first cause of chronic liver disease at the ISSSTE Dr. Valentin Gómez Farias Regional Hospital, both diseases are highly prevalent problems in Mexico and require preventive programs to avoid the high costs and income of third-level care for effect of its complications.
Conflicts of interest: The authors have no conflicts of interest to declare.
