Hepatoblastoma

A 12-month-old male with diagnosis of hepatoblastoma (Figure 1).

Figure 1.

The neoplasm has a solid and nodular growth pattern, divided by thin, fibrous, connective tissue septum.

Hepatoblastoma is the most common malignant tumor of the liver in the pediatric population, affecting mostly young boys age < 3 years and accounting for 75% of primary liver tumors in childhood. Diagnosis is usually at a late stage. Nevertheless, the introduction of chemotherapy with cisplatin and doxorubicin has changed the treatment success of hepatoblastoma substantially, and despite a large tumor mass at presentation, a combined surgical and chemotherapeutic approach has yielded a 5-year survival rateof approximately 80%.