Tratamiento actual del cáncer de próstata de alto riesgo y localmente avanzado
Current treatment in high risk and locally advanced prostate cancer
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Verger-Kuhnke, M.A. Reuter, M.L. Beccaria" "autores" => array:3 [ 0 => array:2 [ "nombre" => "A.B." "apellidos" => "Verger-Kuhnke" ] 1 => array:2 [ "nombre" => "M.A." "apellidos" => "Reuter" ] 2 => array:2 [ "nombre" => "M.L." "apellidos" => "Beccaria" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480607736665?idApp=UINPBA00004N" "url" => "/02104806/0000003100000005/v1_201304251840/S0210480607736665/v1_201304251840/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Tratamiento actual del cáncer de próstata de alto riesgo y localmente avanzado" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "445" "paginaFinal" => "451" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "S. Esquena Fernández, P. Maroto Rey, G. Sancho Pardo, J. Palou Redorta, H. Villavicencio Mavrich" "autores" => array:5 [ 0 => array:4 [ "nombre" => "S." "apellidos" => "Esquena Fernández" "email" => array:1 [ 0 => "dr.esquena@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "cor0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] ] ] 1 => array:3 [ "nombre" => "P." "apellidos" => "Maroto Rey" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "G." "apellidos" => "Sancho Pardo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">***</span>" "identificador" => "aff0015" ] ] ] 3 => array:3 [ "nombre" => "J." "apellidos" => "Palou Redorta" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] ] ] 4 => array:3 [ "nombre" => "H." "apellidos" => "Villavicencio Mavrich" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicio de Urología, Fundació Puigvert" "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicios de Oncología" "etiqueta" => "<span class="elsevierStyleSup">**</span>" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Radioterapia. Hospital Sant Pau. Barcelona" "etiqueta" => "<span class="elsevierStyleSup">***</span>" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia autor: Dr. S. Esquena Servicio de Urología. Fundación Puigvert Cartagena, 340-350. 08025 Barcelona Tel.: 934 169 700" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Current treatment in high risk and locally advanced prostate cancer" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2007-02-01" "fechaAceptado" => "2007-04-01" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec88246" "palabras" => array:4 [ 0 => "Cáncer de próstata" 1 => "Localmente avanzado" 2 => "Alto riesgo" 3 => "Tratamiento" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec88245" "palabras" => array:4 [ 0 => "Prostate cancer" 1 => "Locally advanced" 2 => "High risk" 3 => "Treatment" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">El tratamiento del cáncer de próstata localmente avanzado continúa siendo controvertido. Las opciones terapéuticas comprenden desde la prostatectomía radical (PR), a la radioterapia (RT) y la hormonoterapia (HT). Se ha efectuado una revisión en la base de datos Medline de los trabajos publicados en los últimos 15 años, con las palabras clave en inglés: “cáncer de próstata”, “localmente avanzado”, “alto riesgo” y “tratamiento”. Cincuenta y uno de 329 artículos fueron seleccionados y revisados. El criterio de selección incluía un mínimo nivel de evidencia científica IIa, destacando alguna referencia puntual con evidencia IV. Como demuestran múltiples estudios aleatorios, estos pacientes se pueden beneficiar de una terapia combinada con RT y HT. La PR en enfermedad localmente avanzada ha demostrado su utilidad en algunos casos seleccionados. Los resultados a largo plazo de algunas series son equiparables a los obtenidos con RT y HT. Además, la posibilidad de sobreestadiaje clínico también es un argumento a favor de la PR. Se realiza una revisión actualizada de todas las posibles opciones disponibles en el tratamiento de estos tumores.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Treatment of locally advanced prostate cancer remains controversial. Treatment options include radical prostatectomy (PR), radiotherapy (RT) and hormonotherapy (HT). A Medline database search with key words “prostate cancer”, “locally advanced”, “high risk” and “treatment” in articles published during the last 15 years was done. Fifty one out of 329 papers were selected and reviewed. Selection criteria were a minimum of scientific evidence level of IIa, except for some specific level IV reference. Numerous randomized studies show that patients may benefit of a combined therapy with RT and HT. RP has shown its usefulness in selected cases of locally advanced prostate cancer. Results of long follow-up series are similar to those obtained with RT and HT. Furthermore, the possibility of clinical over staging is an argument in favour of RP. We perform an updated revision of every possible choice available in the treatment of these tumours.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:51 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Prostate cancer. In National Comprehensive Cancer Network (NCCN) Clinical PracticeGuidelines in Oncology, version 2.2005. Jenkinstown, PA: National Comprehensive Cancer Network, June 2006 (<a class="elsevierStyleInterRef" href="http://www.nccn">www.nccn</a>" ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2." 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| año/Mes | Html | Total | |
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| 2024 Octubre | 2 | 18 | 20 |
| 2024 Septiembre | 0 | 10 | 10 |
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| 2023 Octubre | 0 | 24 | 24 |
| 2023 Septiembre | 0 | 7 | 7 |
| 2023 Agosto | 0 | 10 | 10 |
| 2023 Julio | 0 | 60 | 60 |
| 2023 Junio | 0 | 12 | 12 |
| 2023 Mayo | 0 | 6 | 6 |
| 2023 Abril | 0 | 3 | 3 |
| 2023 Marzo | 3 | 8 | 11 |
| 2023 Febrero | 0 | 2 | 2 |
| 2023 Enero | 0 | 6 | 6 |
| 2022 Diciembre | 0 | 8 | 8 |
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| 2022 Octubre | 0 | 16 | 16 |
| 2022 Septiembre | 0 | 12 | 12 |
| 2022 Agosto | 0 | 14 | 14 |
| 2022 Julio | 0 | 13 | 13 |
| 2022 Junio | 0 | 9 | 9 |
| 2022 Mayo | 0 | 19 | 19 |
| 2022 Abril | 0 | 35 | 35 |
| 2022 Marzo | 0 | 28 | 28 |
| 2022 Febrero | 0 | 6 | 6 |
| 2022 Enero | 0 | 5 | 5 |
| 2021 Diciembre | 0 | 7 | 7 |
| 2021 Noviembre | 0 | 3 | 3 |
| 2021 Octubre | 0 | 2 | 2 |
| 2021 Agosto | 0 | 7 | 7 |
| 2021 Julio | 0 | 5 | 5 |
| 2021 Junio | 0 | 1 | 1 |
| 2021 Mayo | 0 | 2 | 2 |
| 2021 Marzo | 0 | 3 | 3 |
| 2021 Febrero | 0 | 3 | 3 |
| 2021 Enero | 0 | 8 | 8 |
| 2020 Diciembre | 0 | 3 | 3 |
| 2020 Noviembre | 0 | 1 | 1 |
| 2020 Octubre | 0 | 5 | 5 |
| 2020 Septiembre | 1 | 5 | 6 |
| 2020 Agosto | 0 | 6 | 6 |
| 2020 Julio | 0 | 2 | 2 |
| 2020 Junio | 0 | 3 | 3 |
| 2020 Mayo | 0 | 10 | 10 |
| 2020 Abril | 0 | 3 | 3 |
| 2020 Marzo | 0 | 4 | 4 |
| 2020 Febrero | 0 | 4 | 4 |
| 2020 Enero | 0 | 10 | 10 |
| 2019 Diciembre | 0 | 19 | 19 |
| 2019 Noviembre | 0 | 1 | 1 |
| 2019 Octubre | 0 | 2 | 2 |
| 2019 Septiembre | 3 | 6 | 9 |
| 2019 Agosto | 0 | 4 | 4 |
| 2019 Julio | 0 | 8 | 8 |
| 2019 Junio | 0 | 15 | 15 |
| 2019 Mayo | 0 | 64 | 64 |
| 2019 Abril | 0 | 28 | 28 |
| 2019 Marzo | 1 | 10 | 11 |
| 2019 Febrero | 0 | 6 | 6 |
| 2019 Enero | 0 | 2 | 2 |
| 2018 Diciembre | 0 | 10 | 10 |
| 2018 Noviembre | 2 | 17 | 19 |
| 2018 Octubre | 0 | 7 | 7 |
| 2018 Febrero | 2 | 3 | 5 |
| 2018 Enero | 0 | 4 | 4 |
| 2017 Noviembre | 1 | 9 | 10 |
| 2017 Octubre | 4 | 13 | 17 |
| 2017 Septiembre | 3 | 5 | 8 |
| 2017 Agosto | 3 | 11 | 14 |
| 2017 Julio | 5 | 13 | 18 |
| 2017 Junio | 7 | 10 | 17 |
| 2017 Mayo | 12 | 9 | 21 |
| 2017 Abril | 17 | 9 | 26 |
| 2017 Marzo | 18 | 12 | 30 |
| 2017 Febrero | 9 | 7 | 16 |
| 2017 Enero | 11 | 6 | 17 |
| 2016 Diciembre | 28 | 12 | 40 |
| 2016 Noviembre | 31 | 7 | 38 |
| 2016 Octubre | 30 | 11 | 41 |
| 2016 Septiembre | 15 | 7 | 22 |
| 2016 Agosto | 14 | 11 | 25 |
| 2016 Julio | 17 | 6 | 23 |
| 2016 Junio | 13 | 12 | 25 |
| 2016 Mayo | 18 | 11 | 29 |
| 2016 Abril | 17 | 6 | 23 |
| 2016 Marzo | 17 | 9 | 26 |
| 2016 Febrero | 14 | 9 | 23 |
| 2016 Enero | 19 | 11 | 30 |
| 2015 Diciembre | 18 | 12 | 30 |
| 2015 Noviembre | 15 | 5 | 20 |
| 2015 Octubre | 19 | 6 | 25 |
| 2015 Septiembre | 13 | 3 | 16 |
| 2015 Agosto | 17 | 6 | 23 |
| 2015 Julio | 10 | 0 | 10 |
| 2015 Junio | 2 | 3 | 5 |
| 2015 Mayo | 11 | 5 | 16 |
| 2015 Abril | 13 | 8 | 21 |
| 2015 Marzo | 13 | 4 | 17 |
| 2015 Febrero | 3 | 3 | 6 |
| 2015 Enero | 9 | 5 | 14 |
| 2014 Diciembre | 17 | 5 | 22 |
| 2014 Noviembre | 11 | 5 | 16 |
| 2014 Octubre | 20 | 3 | 23 |
| 2014 Septiembre | 20 | 1 | 21 |
| 2014 Agosto | 14 | 1 | 15 |
| 2014 Julio | 16 | 1 | 17 |
| 2014 Junio | 17 | 2 | 19 |
| 2014 Mayo | 10 | 1 | 11 |
| 2014 Abril | 7 | 5 | 12 |
| 2014 Marzo | 18 | 2 | 20 |
| 2014 Febrero | 12 | 1 | 13 |
| 2014 Enero | 11 | 3 | 14 |
| 2013 Diciembre | 10 | 2 | 12 |
| 2013 Noviembre | 15 | 3 | 18 |
| 2013 Octubre | 6 | 20 | 26 |
| 2013 Septiembre | 10 | 20 | 30 |
| 2013 Agosto | 5 | 14 | 19 |
| 2013 Julio | 3 | 3 | 6 |
| 2007 Abril | 282 | 0 | 282 |
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