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Inicio Revista Española de Medicina Nuclear e Imagen Molecular (English Edition) Metabolic and osteogenic pattern of prostate cancer bone metastases
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Vol. 32. Issue 1.
Pages 33-36 (January - February 2013)
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Vol. 32. Issue 1.
Pages 33-36 (January - February 2013)
Clinical note
DOI: 10.1016/j.remnie.2012.11.011
Metabolic and osteogenic pattern of prostate cancer bone metastases
Perfil metabólico y osteogénico de las metástasis óseas por cáncer de próstata
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J.R. García
Corresponding author
jrgarcia@cetir.es

Corresponding author.
, E. Riera, E. Valls, M. Soler, M. Moragas, F. Lomeña
Unidad PET/TC, CETIR-ERESA, Esplugues de Llobregat, Barcelona, Spain
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Abstract

The current protocols include the bone scintigraphy and choline PET/CT to localize recurrence in patients having elevated serum PSA after treatment for prostate cancer. Both methods show good agreement in the diagnosis of bone metastases; however, conflicting results can be found. We present three cases in which a PET/CT was performed with 18F-fluoride due to disagreement between the bone scintigraphy and 11C-choline PET/CT. The 18F-fluoride PET/CT was capable of confirming the existence of bone metastasis in all of them, so it may be an alternative to the MRI as a tracer of second bone imaging modality, although its use is limited by cost and availability.

Keywords:
Bone scintigraphy
11C-choline PET/CT
18F-fluoride PET/CT
Prostate cancer recurrence
Bone metastases
Resumen

Los protocolos actuales incluyen a la gammagrafia ósea y a la PET/TC con colina para localizar la recidiva en pacientes tratados por un cáncer de próstata que presentan elevación de PSA sérico. Existe una buena concordancia entre ambos métodos en el diagnóstico de las metástasis óseas, pero puedan darse resultados discordantes. Presentamos 3 casos en los hemos realizado una PET/TC con 18F-fluoruro, ante una discordancia entre la gammagrafia ósea y la PET/TC con 11C-colina. En ellos, el uso de 18F-fluoruro ha podido corroborado la existencia de metástasis óseas, por lo que puede ser una alternativa como trazador de segunda modalidad de imagen ósea a la RM, si bien su uso esta limitado por su coste y disponibilidad.

Palabras clave:
Gammagrafía ósea
11C-colina PET/TC
18F-fluoruro PET/TC
Recurrencia cáncer próstata
Metástasis ósea

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