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Inicio Revista Española de Anestesiología y Reanimación (English Edition) Narcolepsy and opioid-free anesthesia: A review and case report
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Vol. 68. Issue 3.
Pages 165-170 (March 2021)
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Vol. 68. Issue 3.
Pages 165-170 (March 2021)
Review
Narcolepsy and opioid-free anesthesia: A review and case report
Narcolepsia y anestesia libre de opioides: revisión y caso clínico
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5
J.J. Escalona Belmontea,b, S. Romero Molinaa, E. Sepúlveda Haroa, A. Malo Mansoa,b,
Corresponding author
alfredomalomanso@gmail.com

Corresponding author.
, J.L. Guerrero Orriacha,b
a Hospital Universitario Virgen de la Victoria, Málaga, Spain
b Instituto de Investigación Biomédica de Málaga, IBIMA, grupo de investigación A-21, Málaga, Spain
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Abstract
Introduction

Narcolepsy is the second most common sleep disorder. It is characterized by excessive daytime sleepiness together with other symptoms such as cataplexy, sleep paralysis, and hallucinations. The pathophysiology and treatment of this disease, together with its associated syndromes, can severely interfere with anaesthesia.

Methodology

Due to the lack of quality evidence on which to base a high grade of recommendation for anaesthesia in these patients, we performed a non-systematic, narrative review of the literature in Pubmed. We used the descriptors narcolepsy, anaesthesia, surgery, perioperative, opioid, obstructive, apnea and sleep both individually and with AND and OR connectors.

Conclusion

The recommendation to avoid opioids and the stability of opioid-free anaesthesia (OFA) make this approach an option to consider in these patients. We describe a case in which it was used safely.

Keywords:
Narcolepsy
Anaesthesia
Surgery
Perioperative
Opioid
Apnea
Resumen
Introducción

La narcolepsia es el segundo trastorno del sueño en frecuencia y se caracteriza por somnolencia excesiva durante el día junto con otros síntomas como cataplejía, parálisis del sueño y alucinaciones. Su fisiopatología y tratamiento, así como los síndromes que asocia, pueden interferir de forma severa con el acto anestésico.

Metodología

Debido al déficit de evidencia de calidad que aporte un grado de recomendación alto en la anestesia de estos pacientes, se realizó una revisión narrativa de la literatura no sistemática en Pubmed. Como descriptores se usaron narcolepsy, anesthesia, surgery, perioperative, opioid, obstructive, apnea y sleep y se emplearon de forma individual y cruzándolos con conectores AND y OR.

Conclusión

La recomendación de evitar opioides y la estabilidad de la anestesia libre de opioides (OFA), hace de esta última una opción para estos pacientes. Se describe un caso en el que se empleó de forma segura.

Palabras clave:
Narcolepsia
Anestesia
Cirugía
Perioperatoria
Opioide
Apnea

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