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Vol. 60. Issue 3.
Pages 223-229 (May - June 2018)
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Vol. 60. Issue 3.
Pages 223-229 (May - June 2018)
Original Report
Value of dual-energy CT enterography in the analysis of pathological bowel segments in patients with Crohn's disease
Valor de la enterografía por tomografía computarizada con doble energía en el análisis de segmentos intestinales patológicos en pacientes con enfermedad de Crohn
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A.M. Villanueva Campos
Corresponding author
avillanueva@povisa.es

Corresponding author.
, G. Tardáguila de la Fuente, E. Utrera Pérez, C. Jurado Basildo, D. Mera Fernández, C. Martínez Rodríguez
Servicio de Radiología, Hospital Povisa, Vigo, Spain
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Table 1. Demographic characteristics of patients with Crohn's disease included in the study.
Table 2. The average concentrations of iodine density were higher in the pathological segments, and the average concentrations of fat fraction were higher in the healthy segments (p<0.05).
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Abstract
Objective

To analyze whether there are significant differences in the objective quantitative parameters obtained in the postprocessing of dual-energy CT enterography studies between bowel segments with radiologic signs of Crohn's disease and radiologically normal segments.

Material and methods

This retrospective study analyzed 33 patients (16 men and 17 women; mean age 54 years) with known Crohn's disease who underwent CT enterography on a dual-energy scanner with oral sorbitol and intravenous contrast material in the portal phase. Images obtained with dual energy were postprocessed to obtain color maps (iodine maps). For each patient, regions of interest were traced on these color maps and the density of iodine (mg/ml) and the fat fraction (%) were calculated for the wall of a pathologic bowel segment with radiologic signs of Crohn's disease and for the wall of a healthy bowel segment; the differences in these parameters between the two segments were analyzed.

Results

The density of iodine was lower in the radiologically normal segments than in the pathologic segments [1.8±0.4mg/ml vs. 3.7±0.9mg/ml; p<0.05].

The fat fraction was higher in the radiologically normal segments than in the pathologic segments [32.42%±6.5 vs. 22.23%±9.4; p<0.05].

Conclusion

There are significant differences in the iodine density and fat fraction between bowel segments with radiologic signs of Crohn's disease and radiologically normal segments.

Keywords:
Imaging
Dual energy computed tomography
Diagnosis
Crohn disease
Granulomatous enteritis
Mucosa
Resumen
Objetivo

Analizar si existen diferencias significativas en los parámetros cuantitativos obtenidos en el posprocesado de estudios con enterografía por tomografía computarizada (entero-TC) de doble energía entre segmentos intestinales con signos radiológicos de enfermedad de Crohn (EC) y segmentos radiológicamente normales.

Material y métodos

Estudio retrospectivo en el que se analizan 33 pacientes con EC conocida (16 hombres y 17 mujeres), con una media de edad de 54 años. Se seleccionan aquellos con una entero-TC con protocolo de doble energía. Todas las exploraciones están realizadas con una solución de sorbitol oral y contraste intravenoso en fase portal. Mediante técnicas de posprocesado de las imágenes adquiridas con doble energía se obtienen mapas de color (mapas de yodo). Sobre estos mapas de color, mediante la realización de regiones de interés se cuantifican en cada paciente la densidad de yodo (mg/ml) y la fracción de grasa (%) de la pared de un segmento intestinal patológico con signos radiológicos de EC y de un segmento sano, y se analiza si existen diferencias entre ambos.

Resultados

La cuantificación de yodo en los segmentos sanos es 1,8 (± 0,4) mg/ml, y en los segmentos enfermos es 3,7 (± 0,9) mg/ml (p <0,05). La fracción de grasa presente en la pared de los segmentos sanos es del 32,42% (± 6,5), y en los segmentos afectados es del 22,23% (± 9,4) (p <0,05).

Conclusión

Existen diferencias significativas en la cuantificación de la densidad de yodo y la fracción de grasa entre segmentos intestinales con signos radiológicos de EC y segmentos radiológicamente normales.

Palabras clave:
Imagen
Tomografía computarizada de doble energía
Diagnóstico
Enfermedad de Crohn
Enteritis granulomatosa
Mucosa

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