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Vol. 26. Issue 5.
Pages 297-300 (January 2011)
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Vol. 26. Issue 5.
Pages 297-300 (January 2011)
Full text access
Effects of the fluoride on the central nervous system
Efectos del flúor sobre el sistema nervioso central
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L. Valdez-Jiméneza, C. Soria Fregozoa,
Corresponding author
, M.L. Miranda Beltránb, O. Gutiérrez Coronadob, M.I. Pérez Vegaa
a Laboratorio de Psicobiología, Departamento de Ciencias de la Tierra y de la Vida, Centro Universitario de los Lagos, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico
b Laboratorio de Aplicaciones Biomédicas, Departamento de Ciencias de la Tierra y de la Vida, Centro Universitario de los Lagos, Universidad de Guadalajara, Jalisco, Mexico
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Abstract
Introduction

Fluorine (F) is a toxic reactive element and exposure to it passes almost unnoticed with the consumption of tea, fish, meat, fruits, etc. and articles in common use such as: toothpaste additives; dental gels, non-stick pans and razor blades as Teflon. It has also been used with the intention of reducing dental caries.

Development

Fluoride can accumulate in the body, and it has been shown that continuous exposure to it causes damaging effects on body tissues, particularly the nervous system directly without any previous physical malformations.

Background

Several clinical and experimental studies have reported that F induces changes in cerebral morphology and biochemistry that affect the neurological development of individuals as well as cognitive processes, such as learning and memory.

F can be toxic by ingesting one part per million (ppm), and the effects are not immediate, as they can take 20 years or more to become evident.

Conclusion

The prolonged ingestion of F may cause significant damage to health and particularly to the nervous system. Therefore, it is important to be aware of this serious problem and avoid the use of toothpaste and items that contain F, particularly in children as they are more susceptible to the toxic effects of F.

Keywords:
Fluoride
Health
Nervous system
Resumen
Introducción

El flúor (F) es un elemento tóxico y reactivo; la exposición al mismo pasa casi inadvertida con el consumo de té, pescado de mar, carnes, frutas, etc., y el uso de artículos como aditivo en pastas de dientes, enjuagues bucales, antiadherentes sobre sartenes y hojas de afeitar como el teflón. Asimismo, ha sido utilizado con la intención de reducir la caries dental.

Desarrollo

El F puede acumularse en el organismo y se ha demostrado que la exposición crónica al mismo produce efectos nocivos sobre distintos tejidos del organismo y de manera particular sobre el sistema nervioso, sin producir malformaciones físicas previas.

Fuentes

Diversos trabajos, tanto clínicos como experimentales, han reportado que el F provoca alteraciones sobre la morfología y bioquímica cerebral, que afectan el desarrollo neurológico de los individuos y, por ende, de funciones relacionadas con procesos cognoscitivos, tales como el aprendizaje y la memoria.

La toxicidad del F se puede presentar a partir de la ingesta de 1 parte por millón (ppm) y los efectos no son inmediatos ya que pueden tardar 20 años o más en manifestarse.

Conclusión

La ingesta prolongada de F provoca daños a la salud y de manera importante sobre el sistema nervioso central, por lo que es importante considerar y evitar el uso de artículos que contengan flúor y de manera particular en individuos en desarrollo, debido a la susceptibilidad que presentan a los efectos tóxicos del F.

Palabras clave:
Flúor
Salud
Sistema nervioso
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Copyright © 2011. Sociedad Española de Neurología
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