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Inicio Neurología (English Edition) Clinical profile, antibiotic treatment, and risk of stroke in patients with infe...
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Vol. 38. Issue 6.
Pages 443 (July - August 2023)
Vol. 38. Issue 6.
Pages 443 (July - August 2023)
Letter to the Editor
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Clinical profile, antibiotic treatment, and risk of stroke in patients with infective endocarditis
Perfil clínico, tratamiento antibiótico y riesgo de ictus en pacientes con endocarditis infecciosa
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M. Martínez-Sellés
Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, CIBERCV, Universidad Europea, Universidad Complutense, Madrid, Spain
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I read with great interest the article by Rodríguez-Montolio et al.1 on the prevalence of stroke among patients with endocarditis. The authors describe the differences in baseline characteristics between patients with and without stroke; this is an important consideration, as several clinical predictors of acute cerebrovascular accident have been identified in patients with infective endocarditis.2 For instance, in the prospective registry of the Spanish Collaboration on Endocarditis group (GAMES, for its Spanish initials), 17% of diabetic patients presented stroke during hospitalisation due to infective endocarditis, compared to 11% of patients without diabetes.3 Unfortunately, the authors do not include information on diabetes or other clinical characteristics, which would have been valuable, given that this information is easy to obtain. The authors also do not compare the onset of antibiotic treatment in patients with and without stroke. This information is highly relevant, as previous studies have shown a clear association between delayed onset of antibiotic treatment and the risk of stroke.4

Conflicts of interest

The author has no conflicts of interest to declare.

References
[1]
J. Rodríguez-Montolio, D. Meseguer-Gonzalez, M. Almeida-Zurita, P. Revilla-Martí, S. Santos-Lasaosa.
Prevalence of neurological complications in infective endocarditis.
Neurologia (Engl Ed)., (2022),
[2]
I. Valenzuela, M.D. Hunter, K. Sundheim, B. Klein, L. Dunn, R. Sorabella, et al.
Clinical risk factors for acute ischaemic and haemorrhagic stroke in patients with infective endocarditis.
Intern Med J., 48 (2018), pp. 1072-1080
[3]
M.I. Biezma, P. Muñoz, S. De la Villa, M.C. Fariñas-Álvarez, F. Arnáiz de las Revillas, E. Gutierrez-Carretero, et al.
Infective endocarditis in diabetic patients: a different profile with prognostic consequences.
J Clin Med., 11 (2022), pp. 2651
[4]
S.A. Dickerman, E. Abrutyn, B. Barsic, E. Bouza, E. Cecchi, A. Moreno, et al.
ICE Investigators. The relationship between the initiation of antimicrobial therapy and the incidence of stroke in infective endocarditis: an analysis from the ICE Prospective Cohort Study (ICE-PCS).
Am Heart J., 154 (2007), pp. 1086-1094
Copyright © 2022. Sociedad Española de Neurología
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es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos

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