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Inicio Medicina Clínica (English Edition) Use of the CHADS2 score as a predictor of the risk of mortality in hypertensive ...
Journal Information
Vol. 146. Issue 11.
Pages 478-483 (June 2016)
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Vol. 146. Issue 11.
Pages 478-483 (June 2016)
Original article
DOI: 10.1016/j.medcle.2016.07.002
Use of the CHADS2 score as a predictor of the risk of mortality in hypertensive patients. The FAPRES study
Uso de la escala CHADS2 como predictor de riesgo de mortalidad en pacientes hipertensos. El estudio FAPRES
Elena Castillaa,
Corresponding author

Corresponding author.
, Pedro Morillasa, Manuel Gómeza, Miguel Ahumadaa, Marta Monteagudoa, Lorenzo Fácilab, Vicente Pallaresc
a Servicio de Cardiología, Hospital General Universitario de Elche, Elche, Alicante, Spain
b Servicio de Cardiología, Hospital General de Valencia, Valencia, Spain
c Unidad de Vigilancia de la Salud, Unión de Mutuas, Departamento de Medicina, Universitat Jaume I, Castellón, Spain
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Figures (4)
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Tables (4)
Table 1. Baseline characteristics of the population according to the CHADS2 score.
Table 2. Comparative study between patients according to follow-up mortality.
Table 3. Multivariate analysis. Factors associated with overall mortality during follow-up.
Table 4. Multivariate analysis. Factors associated with cardiovascular mortality during follow-up.
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Foundations and aim

The aim of this study is to analyze the CHADS2 score as a marker of the risk of mortality in hypertensive patients, with and without the presence of atrial fibrillation.


We included 1003 hypertensive patients ≥65 years. Risk factors, and CHADS2 score were recorded among other factors, as well as clinical follow-up of number and type of deaths.


Mean age was 72.8±5.8 years, and 47.5% were men. During follow-up there were 41 deaths, 20 were of cardiovascular origin. Patients with higher CHADS2 had a higher mortality: 1.5% CHADS2=1; 4.7% in CHADS2=2; 9.1% in CHADS2=3, and 7.8% in CHADS24.


The CHADS2 score can be a clinical instrument of easy application to identify hypertensive patients with a high risk of mortality.

Cardiovascular mortality
Fundamentos y objetivo

El objetivo del estudio es analizar la escala CHADS2 como marcador de riesgo de mortalidad en pacientes hipertensos, independientemente de la presencia o no de fibrilación auricular.


Se incluyó a 1.003 pacientes hipertensos ≥ 65 años, recogiendo factores de riesgo y puntuación CHADS2. Se realizó un seguimiento clínico de la mortalidad.


La media de edad de la población fue 72,8 ± 5,8 años; el 47,5% eran varones. Durante el seguimiento hubo 41 muertes, 20 de origen cardiovascular. Los pacientes con mayor CHADS2 tuvieron una mayor mortalidad: 1,5% en CHADS2 = 1; 4,7% en CHADS2 = 2; 9,1% en CHADS2 = 3, y 7,8% en CHADS2 ≥ 4.


La puntuación CHADS2 puede ser un instrumento clínico de sencilla aplicación para identificar pacientes hipertensos con alto riesgo de mortalidad.

Palabras clave:
Mortalidad cardiovascular
Hipertensión arterial
Coagulación arterial


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