Buscar en
Medicina Clínica (English Edition)
Toda la web
Inicio Medicina Clínica (English Edition) Pyoderma gangrenosum: Classic and emerging therapies
Journal Information
Vol. 149. Issue 6.
Pages 256-260 (September 2017)
Share
Share
Download PDF
More article options
ePub
Visits
0
Vol. 149. Issue 6.
Pages 256-260 (September 2017)
Review
DOI: 10.1016/j.medcle.2017.08.007
Pyoderma gangrenosum: Classic and emerging therapies
Pioderma gangrenoso: terapias clásicas y emergentes
Visits
...
Felipe Soto Vilchesa, Cristián Vera-Kelletb,
Corresponding author
cristianverakellet@gmail.com

Corresponding author.
a Departamento de Dermatología, Hospital Clínico Universidad de Chile, Santiago, Chile
b Departamento de Dermatología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile
Article information
Abstract
Full Text
Bibliography
Download PDF
Statistics
Figures (3)
Show moreShow less
Abstract

Pyoderma gangrenosum is an ulceronecrotising dermatosis that represents a challenge for any clinician, not only for its ability to mimic other dermatoses but also for its lack of response to treatment. During the past year, there have been new studies about the efficacy of standard therapies, such as cyclosporine and systemic corticosteroids. These studies showed that classic treatment was comparable, but they are insufficient as monotherapy. That being said, new emerging therapies are becoming important, as the use of corticosteroid-sparing agents, tumour necrosis factor inhibitors or even surgery. This review updates the current evidence for the treatment of pyoderma gangrenosum.

Keywords:
Pyoderma gangrenosum
Treatment
Cyclosporine
Tumour necrosis factor inhibitors
Steroids
Resumen

El pioderma gangrenoso es una dermatosis ulceronecrótica que representa un desafío importante para el clínico no solo porque puede simular otras dermatosis, sino porque en general no responde a los tratamientos habituales. Durante el último año han surgido nuevos estudios acerca de la eficacia real de los tratamientos convencionales, tales como la ciclosporina y los glucocorticoides sistémicos. Estos estudios han demostrado que los tratamientos clásicos son comparables pero insuficientes como monoterapia. Han surgido nuevos tratamientos, como los agentes ahorradores de glucocorticoides, los inhibidores del factor de necrosis tumoral y la cirugía. Esta revisión es una puesta al día de la evidencia actual para el tratamiento del pioderma gangrenoso.

Palabras clave:
Pioderma gangrenoso
Tratamiento
Ciclosporina
Inhibidores del factor de necrosis tumoral
Corticosteroides

Article

These are the options to access the full texts of the publication Medicina Clínica (English Edition)
Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe
Subscribe to

Medicina Clínica (English Edition)

Comprar
Comprar acceso al artículo

Comprando el artículo el PDF del mismo podrá ser descargado

Precio 19,34 €

Comprar ahora
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
E-mail
Article options
Tools
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos