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Inicio Medicina Clínica (English Edition) Progression over time of changes in anticoagulant treatment in a tertiary hospit...
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Vol. 156. Issue 3.
Pages 135-138 (February 2021)
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Vol. 156. Issue 3.
Pages 135-138 (February 2021)
Clinical report
DOI: 10.1016/j.medcle.2020.07.020
Progression over time of changes in anticoagulant treatment in a tertiary hospital
Evolución temporal de los cambios en el tratamiento anticoagulante en un hospital terciario
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Paula Hernández, Lucia Polanco, Ignacio Santiago, Marina Fayos, Carmen Valero
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mirvdc@humv.es

Corresponding author.
Departamento de Medicina Interna, Hospital Universitario Marqués de Valdecilla, IDIVAL, Universidad de Cantabria, Santander, Spain
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Table 1. Profile of anticoagulated patients in both periods.
Table 2. Characteristics of anticoagulated patients in 2018.
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Abstract
Introduction

The use of direct oral anticoagulants (DOACs) has modified anticoagulant therapy guidelines.

Objectives

To determine changes and trends in the anticoagulant therapy of inpatients at an Internal medicine department.

Material and methods

1584 inpatients of the internal medicine department (Hospital Marqués de Valdecilla. Santander) were studied in 2008 and 2018. The use of anticoagulant treatment, type of treatment, atrial fibrillation, comorbidity index, thrombotic and haemorrhagic complications were collected from the discharge reports.

Results

The prevalence of anticoagulants increased by 5.7% (13.1% to 18.8%; p=0.002). The mean age increased by 7 years (76.2±11.1 yrs. vs. 83.6±8.9 yrs; p<0.001). The percentage of anticoagulated patients older than 75 yrs doubled. In 2018, 52% of anticoagulated in patients took an DOAC. The prevalence of atrial fibrillation increased by 4% (30% vs. 34%; p=0.04) and by 24% that of anticoagulated atrial fibrillation by 24% (32.3% vs. 56%; p=7.2×10-8). The mean age is 6 years older (78.4±8.2 vs. 84.2±8.0; p<0.001).

Conclusions

The percentage of anticoagulated patients in internal medicine has increased, especially in those with atrial fibrillation.

Keywords:
Anticoagulation
Atrial fibrillation
Direct oral anticoagulants
Resumen
Introducción

Los anticoagulantes orales de acción directa (ACOD) han modificado el tratamiento anticoagulante.

Objetivos

Conocer los cambios y tendencias producidos en la anticoagulación en medicina interna.

Material y métodos

Se estudiaron 1.584 ingresos en medicina interna (Hospital Marqués de Valdecilla. Santander) en 2008 y 2018. Se recogió el tratamiento anticoagulante, indicación y tipo, fibrilación auricular, complicaciones a 6 meses y mortalidad a 2 años.

Resultados

La prevalencia de anticoagulados aumentó un 5,7% (13,1% vs. 18,8%; p=0,002), la media de edad fue 7 años mayor (76,2±11,1 vs. 83,6±8,9; p<0,001). Se duplicaron los anticoagulados mayores de 75 años. En el 2018 el 52% de los anticoagulados tomaban un ACOD. En 10 años aumentó la prevalencia de fibrilación auricular un 4% (30% vs. 34%; p=0,04) y la de fibrilación auricular anticoagulada un 24% (32,3% vs. 56%; p<0,001). La media de edad fue 6 años mayor (78,4±8,2 vs. 84,2±8,0; p<0,001).

Conclusiones

Ha aumentado el porcentaje de pacientes anticoagulados en medicina interna, sobre todo en aquellos con fibrilación auricular.

Palabras clave:
Anticoagulación
Fibrilación auricular
Anticoagulantes orales de acción directa

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