Buscar en
Medicina Clínica (English Edition)
Toda la web
Inicio Medicina Clínica (English Edition) Influence of influenza vaccine and comorbidity on the evolution of hospitalized ...
Journal Information
Vol. 158. Issue 12.
Pages 603-607 (June 2022)
Share
Share
Download PDF
More article options
ePub
Visits
7
Vol. 158. Issue 12.
Pages 603-607 (June 2022)
Brief report
Influence of influenza vaccine and comorbidity on the evolution of hospitalized COVID-19 patients⋆
Influencia de la vacunación antigripal y la comorbilidad en la evolución de los pacientes hospitalizados por COVID-19
Visits
...
José Manuel Fernández Ibáñeza,
Corresponding author
jmfernandezi@sescam.jccm.es

Corresponding author.
, María del Carmen Morales Ballesterosa, Manuel José Fernández Anguitab, María Ángeles Galindo Andúgard, Ángel Arias Ariasc, José Ramón Barberá-Farréd
a Servicio de Medicina Interna, Sección Geriatría, Hospital General Mancha Centro, Alcázar de San Juan, Spain
b Servicio de Cardiología, Hospital General Mancha Centro, Alcázar de San Juan, Spain
c Unidad de Investigación, Hospital General Mancha Centro, Alcázar de San Juan, Spain
d Servicio de Medicina Interna, Hospital General Mancha Centro, Alcázar de San Juan, Spain
Article information
Abstract
Full Text
Bibliography
Download PDF
Statistics
Abstract
Background and objective

The COVID-19 coronavirus disease outbreak is evolving around the world. Objective: To evaluate the associations between influenza vaccination and other factors and the risk of mortality in hospitalized COVID-19 patients.

Materials and methods

Retrospective observational study. This study was conducted among hospitalized patients with COVID-19 at Hospital La Mancha Centro between March 5 and 25, 2020. Information on influenza vaccination was extracted from electronic medical records. We used a multivariate logistic regression to explore the association between influenza vaccination and mortality from COVID and other risk factors.

Results

410 patients were included. Influenza vaccine had no effect among COVID-19 hospitalized patients [OR: 1.55 (95%CI: 0.96–2.48; p = 0.071)]. Increasing hospital mortality was associated with older age [OR: 1.05 (95% CI 1.02–1.07), per year increase; p < 0.001)], Charlson ≥3 [OR: 1.84 (95%CI: 1.07–3.15, p = 0.027)] and heart failure on admission [OR: 6 (IC95%: 1.6–21.7; p = 0.007)].

Conclusions

Influenza vaccine had no effect among COVID-19 hospitalized patients. The risk factors identified were older age, higher comorbidity and heart failure on admission.

Keywords:
Influenza vaccine
COVID-19
Hospitalized patients
Age
Comorbidity
Mortality
Resumen
Antecedentes y objetivo

El brote de la enfermedad COVID-19 está evolucionando en todo el mundo. Objetivo: Evaluar la asociación de la vacunación antigripal y otros factores y el riesgo de mortalidad en pacientes con COVID-19 hospitalizados.

Materiales y métodos

Estudio observacional retrospectivo. Se realizó entre pacientes hospitalizados con COVID-19 del Hospital La Mancha Centro entre el 5 y el 25 de marzo de 2020. Utilizamos una regresión logística multivariable para explorar la asociación entre la vacunación antigripal y la mortalidad por COVID y otros factores de riesgo.

Resultados

Se incluyeron 410 pacientes. La vacunación antigripal no tuvo efecto entre los pacientes hospitalizados por COVID-19 [OR: 1,55 (IC95%: 0,96–2,48; p = 0,071)]. El aumento de la mortalidad intrahospitalaria se asoció con edad avanzada [OR: 1,05, (IC95%: 1,02–1,07), por cada aumento de año; p < 0.001)], Charlson ≥ 3 [OR: 1,84 (IC95%: 1,07–3,15, p = 0,027)] e insuficiencia cardíaca al ingreso [OR: 6 (IC95%: 1,6–21,7; p = 0,007)].

Conclusiones

La vacuna antigripal no tuvo efecto en la evolución de pacientes hospitalizados por COVID-19. Los factores de riesgo identificados fueron la edad avanzada, mayor comorbilidad e insuficiencia cardíaca al ingreso.

Palabras clave:
Vacuna antigripal
COVID-19
Pacientes hospitalizados
Edad
Comorbilidad
Mortalidad

Article

These are the options to access the full texts of the publication Medicina Clínica (English Edition)
Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe
Subscribe to

Medicina Clínica (English Edition)

Purchase
Purchase article

Purchasing article the PDF version will be downloaded

Price 19.34 €

Purchase now
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
E-mail
Article options
Tools
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos