One-Step Nucleic Acid Amplification (OSNA) Assay for Sentinel Lymph Node Metastases as an Alternative to Conventional Postoperative Histology in Breast Cancer: A Cost-Benefit Analysis

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Original Article

El análisis molecular intraoperatorio (one-step nucleic acid amplification) del ganglio centinela como alternativa al estudio histopatológico diferido en el cáncer de mama: análisis coste-beneficio

María Pilar Guillén-Paredesa,

Corresponding author

magirapi@hotmail.com

Corresponding author.

, Luis Carrasco-Gonzáleza, Asunción Cháves-Benitob, Álvaro Campillo-Sotoa, Andrés Carrilloc, José Luis Aguayo-Albasinia

a Servicio Cirugía General y Digestivo, Hospital Morales Meseguer, Murcia, Spain

b Servicio Anatomía Patológica, Hospital Morales Meseguer, Murcia, Spain

c Servicio Medicina Intensiva, Hospital Morales Meseguer, Murcia, Spain

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Article information

ISSN: 21735077
Original language: English

DOI:10.1016/j.cireng.2011.04.004

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Year/Month	Html	Pdf	Total

2025 12	65	2	67
2025 11	159	21	180
2025 10	99	13	112
2025 9	74	10	84
2025 8	77	14	91
2025 7	98	5	103
2025 6	103	11	114
2025 5	85	4	89
2025 4	113	2	115
2025 3	89	5	94
2025 2	41	2	43
2025 1	38	0	38
2024 12	42	5	47
2024 11	53	4	57
2024 10	34	6	40
2024 9	58	1	59
2024 8	32	5	37
2024 7	42	7	49
2024 6	38	0	38
2024 5	32	2	34
2024 4	23	7	30
2024 3	55	3	58
2024 2	50	2	52
2024 1	57	8	65
2023 12	57	9	66
2023 11	106	8	114
2023 10	87	6	93
2023 9	32	4	36
2023 8	52	3	55
2023 7	59	2	61
2023 6	83	5	88
2023 5	74	2	76
2023 4	75	8	83
2023 3	52	3	55
2023 2	42	5	47
2023 1	38	6	44
2022 12	40	6	46
2022 11	55	10	65
2022 10	36	8	44
2022 9	42	9	51
2022 8	37	11	48
2022 7	37	33	70
2022 6	43	4	47
2022 5	41	9	50
2022 4	52	15	67
2022 3	38	12	50
2022 2	79	5	84
2022 1	72	10	82
2021 12	59	9	68
2021 11	49	8	57
2021 10	77	16	93
2021 9	27	12	39
2021 8	48	7	55
2021 7	20	7	27
2021 6	35	13	48
2021 5	46	11	57
2021 4	87	19	106
2021 3	67	11	78
2021 2	44	13	57
2021 1	37	15	52
2020 12	33	10	43
2020 11	41	6	47
2020 10	27	5	32
2020 9	36	10	46
2020 8	43	8	51
2020 7	37	11	48
2020 6	30	3	33
2020 5	52	8	60
2020 4	36	4	40
2020 3	148	7	155
2020 2	126	4	130
2020 1	113	8	121
2019 12	72	13	85
2019 11	79	17	96
2019 10	51	9	60
2019 9	45	12	57
2019 8	39	6	45
2019 7	35	16	51
2019 6	47	16	63
2019 5	112	7	119
2019 4	56	4	60
2019 3	9	3	12
2019 2	9	5	14
2019 1	5	5	10
2018 12	6	4	10
2018 11	10	7	17
2018 10	17	2	19
2018 9	16	4	20
2018 8	11	1	12
2018 7	13	1	14
2018 6	4	2	6
2018 5	7	3	10
2018 4	13	9	22
2018 3	13	0	13
2018 2	3	3	6
2018 1	10	4	14
2017 12	7	1	8
2017 11	16	1	17
2017 10	18	1	19
2017 9	16	6	22
2017 8	5	4	9
2017 7	9	2	11
2017 6	8	3	11
2017 5	16	2	18
2017 4	14	0	14
2017 3	18	17	35
2017 2	8	5	13
2017 1	17	2	19
2016 12	17	8	25
2016 11	9	9	18
2016 10	21	8	29
2016 9	32	9	41
2016 8	17	14	31
2016 7	13	1	14
2016 6	23	10	33
2016 5	20	14	34
2016 4	8	13	21
2016 3	21	23	44
2016 2	12	8	20
2016 1	10	6	16
2015 12	9	6	15
2015 11	20	9	29
2015 10	20	7	27
2015 9	28	6	34
2015 8	18	4	22
2015 7	17	4	21
2015 6	12	4	16
2015 5	18	4	22
2015 4	31	4	35
2015 3	21	8	29
2015 2	33	6	39
2015 1	45	13	58
2014 12	53	14	67
2014 11	31	9	40
2014 10	50	7	57
2014 9	42	7	49
2014 8	34	7	41
2014 7	32	3	35
2014 6	15	7	22
2014 5	21	2	23
2014 4	35	8	43
2014 3	18	8	26
2014 2	33	2	35
2014 1	40	5	45
2013 12	24	5	29
2013 11	21	3	24
2013 10	32	10	42
2013 9	27	5	32
2013 8	26	4	30
2013 7	11	6	17

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