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Inicio Archivos de la Sociedad Española de Oftalmología (English Edition) Intense pulsed light therapy: A promising complementary treatment for dry eye di...
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Vol. 94. Issue 7.
Pages 331-336 (July 2019)
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Vol. 94. Issue 7.
Pages 331-336 (July 2019)
Original article
DOI: 10.1016/j.oftale.2019.03.003
Intense pulsed light therapy: A promising complementary treatment for dry eye disease
Terapia de luz pulsada intensa regulada: un tratamiento complementario prometedor para la enfermedad de ojo seco
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L.F. Mejíaa,b,
Corresponding author
lfmejia@lfmejia.com

Corresponding author.
, J.C. Gilb, M. Jaramilloc
a Head Cornea Service, School of Medicine, CES University, Medellín, Colombia
b Ophthalmology Research Service, School of Medicine, CES University, Medellín, Colombia
c Ophthalmology Service, School of Medicine, CES University, Medellín, Colombia
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Table 1. Subgroup analysis: Rosacea and Sjögren.
Abstract
Objective

To propose the intense pulsed light (IPL) therapy as a helpful supplementary treatment in patients with dry eye disease.

Material and methods

Retrospective cross sectional design. Medical records of patients in whom dry eye disease symptoms were not satisfactorily controlled with medical therapy alone and who underwent additional IPL therapy, and tree sessions were completed. Data were analyzed before therapy and 3 weeks after its completion to assess improvement. Determination of symptoms, through a visual analog scale; tear film stability, through tear Break Up Time (tBUT); measurement of tear secretion, through Schirmer Test; and ocular surface staining with Van Bijsterveld score were evaluated. SPSS software and nonparametric analysis of repeated measures were used. The study was approved by the ethics committee.

Results

50 eyes from 25 subjects were reviewed. There were 9 males (36%) and 16 females (64%), with a median age of 59 years (IQR 52–64). The median of the symptoms scale was 8 (IQR 8–9) and 3 (IQR 2–4) before and after the therapy respectively (p<0.05). The median of BUT was 4 (IQR 3–5) and 10 (IQR 8–11), Schirmer test was 13 (IQR 12–15) and 15 (IQR 13–20), and Van Bijsterveld score was 3 (RIC 3–4) and 2 (IQR 2–3) before and after the therapy respectively (p<0.05, for all measurements).

Conclusion

IPL treatment has excellent results regarding both: dry eye disease symptoms improvement and in office objective tests such as tBUT, Schirmer test and Van Bijsterveld score; IPL could be considered as an effective adjunct for dry eye disease.

Keywords:
Pulsed light therapy
Dry eye
Rosacea
Sjögren's syndrome
Meibomian gland dysfunction
Resumen
Objetivo

Presentar los resultados del tratamiento con luz pulsada regulada (IPL) en pacientes con ojo seco.

Material y métodos

Estudio retrospectivo. Se analizaron historias clínicas de pacientes con ojo seco sometidos a terapia IPL en quienes no se logró un control satisfactorio de los síntomas luego de terapia médica. Se evaluó previo al inicio y al final de la terapia una escala analógica visual de síntomas y además el tiempo de rotura de la película lagrimal (tBUT), test de Schirmer y puntaje de Van Bijsterveld. Se realizó un análisis de medidas repetidas con SPSS comparando los resultados antes y después de realizar la terapia IPL.

Resultados

Se analizaron 50 ojos de 25 pacientes: 9 hombres (36%) y 16 mujeres (64%); se encontró una mediana de edad de 59años (RIC 52-64). La mediana en la escala de síntomas fue de 8 (RIC 8-9) y 3 (RIC 2-4) antes y después del tratamiento con IPL (p<0,05). El tBUT tuvo una mediana de 4 (RIC 3-5) y 10 (RIC 8-11), el test de Schirmer de 13 (RIC 12-15) y 15 (RIC 13-20) y el puntaje de Van Bijsterveld de 3 (RIC 3-4) y 2 (RIC 2-3) antes y después del tratamiento, respectivamente (p<0,05 en todos los análisis).

Conclusiones

La terapia de IPL para el ojo seco es una excelente opción de tratamiento: muestra mejoría objetiva mediante la estabilización de la película lagrimal y tinción de superficie ocular, así como también mejoría subjetiva evidenciada en los síntomas manifestados por los pacientes.

Palabras clave:
Terapia de luz pulsada
Ojo seco
Rosácea
Síndrome de Sjögren
Disfunción de glándulas de Meibomio

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