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Inicio Archivos de la Sociedad Española de Oftalmología (English Edition) Granulomatosis with polyangiitis confined to lacrimal gland, a case report
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Vol. 92. Issue 11.
Pages 543-546 (November 2017)
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Vol. 92. Issue 11.
Pages 543-546 (November 2017)
Short communication
Granulomatosis with polyangiitis confined to lacrimal gland, a case report
Granulomatosis con poliangeítis localizado en la glándula lagrimal, a propósito de un caso
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F. Zuazoa,
Corresponding author
franzuazo@gmail.com

Corresponding author.
, M. Gonzáleza, A. Abdalaa, O. Olvera-Moralesa, M.H. Monroya, A. Rodríguez-Reyesb, J.L. Tovilla-Canalesa, Á. Nava-Castañedaa
a Instituto de Oftalmología «Fundación de Asistencia Privada Conde de Valenciana IAP», Mexico City, Mexico
b Servicio de Patología Oftálmica, Asociación para Evitar la Ceguera en México IAP, Hospital «Dr. Luis Sánchez Bulnes» , Mexico City, Mexico
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Abstract
Clinical case

A 43 year-old woman consulted due to 2 months of swelling on the superolateral side of the left orbit, with pain and erythema. An excisional biopsy was performed that revealed vasculitis with polyangiitis of the lacrimal gland. A systemic study showed that no other system was compromised.

Discussion

Orbital involvement occurs in up to 60% of patients with granulomatosis with polyangiitis. The involvement of the lacrimal gland is rare and often unilateral. Serological tests are generally negative, both in initial stages, as in localized forms of the disease.

Keywords:
Granulomatosis with polyangiitis
Necrotizing vasculitis
Anti-neutrophil cytoplasm antibody
Resumen
Caso clínico

Mujer de 43 años, consulta por aumento de volumen orbitario superolateral izquierdo, doloroso, eritematoso de 2 meses de evolución. Se realiza biopsia escisional revelando vasculitis con poliangeítis de glándula lagrimal. El estudio sistémico no reveló compromiso de otros órganos.

Discusión

El compromiso orbitario ocurre hasta en el 60% de los pacientes con granulomatosis con poliangeítis. La afección de la glándula lagrimal es rara, y frecuentemente unilateral. Las pruebas serológicas generalmente son negativas, tanto en etapas iniciales, como en las formas localizadas de la enfermedad.

Palabras clave:
Granulomatosis con poliangeítis
Vasculitis necrotizante
Anticuerpo anti-citoplasma de neutrófilos

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