Buscar en
Allergologia et Immunopathologia
Toda la web
Inicio Allergologia et Immunopathologia Tear and serum vitamin D levels in children with allergic rhinoconjunctivitis
Journal Information
Vol. 43. Issue 6.
Pages 533-537 (November - December 2015)
Share
Share
Download PDF
More article options
ePub
Vol. 43. Issue 6.
Pages 533-537 (November - December 2015)
Original Article
DOI: 10.1016/j.aller.2014.10.004
Tear and serum vitamin D levels in children with allergic rhinoconjunctivitis
Visits
...
Sevil Bilir Goksugura,
Corresponding author
sevilbilir@yahoo.com

Corresponding author.
, Mesut Erdurmusb, Mervan Bekdasa, Mustafa Erkocogluc, Sumeyra Agcab, Mehmet Tosund, Nadir Goksugure, Fatih Demircioglua
a Department of Pediatrics, Medical Faculty, Abant Izzet Baysal University, Bolu, Turkey
b Department of Ophthalmology, Medical Faculty, Abant Izzet Baysal University, Bolu, Turkey
c Department of Pediatric Allergy, Medical Faculty, Abant Izzet Baysal University, Bolu, Turkey
d Department of Biochemistry, Medical Faculty, Abant Izzet Baysal University, Bolu, Turkey
e Department of Dermatology, Medical Faculty, Abant Izzet Baysal University, Bolu, Turkey
Article information
Abstract
Full Text
Bibliography
Download PDF
Statistics
Figures (1)
Tables (2)
Table 1. Demographic and clinical characteristics of the groups.
Table 2. Tear and serum vitamin D levels and serum total IgE levels of both groups.
Show moreShow less
Abstract
Background

Although solid cohort studies confirmed a preventative role for the anti-oxidant vitamin D in allergic asthma, a limited number of studies focused on allergic rhinoconjunctivitis (ARC). Here, we aimed to determine 25-hydroxycholecalciferol levels in tear and serum in young allergic rhinoconjunctivitis patients as compared to their apparently healthy matched controls.

Methods

In total, 22 children with allergic rhinoconjunctivitis and 31 healthy control subjects underwent serum total IgE and 25-hydroxycholecalciferol measurements. Tear levels of 25-hydroxycholecalciferol were also determined in both groups.

Results

The mean serum total IgE level in the ARC group (143.6±132.8IU/ml) was significantly higher than that in the control group (54.8±44.1IU/ml; p=0.03). Serum 25(OH)D levels were significantly higher in the ARC group (34.1±12.7ng/ml) than in the healthy controls (21.8±11.3ng/ml; p=0.001).

Conclusions

To our knowledge, this is the first reported study to show an association between serum 25-hydroxycholecalciferol and ARC in a childhood group. Higher levels of serum 25-hydroxycholecalciferol in children with allergic rhinoconjunctivitis may indicate a possible aetiopathogenic mechanism in the development of allergic rhinoconjunctivitis. This is also the first report to examine tear fluid vitamin D levels in paediatric ARC patients.

Keywords:
Allergic rhinoconjunctivitis
Immunoglobulin E
Tear
Vitamin D

Article

These are the options to access the full texts of the publication Allergologia et Immunopathologia
Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe
Subscribe to

Allergologia et Immunopathologia

Comprar
Comprar acceso al artículo

Comprando el artículo el PDF del mismo podrá ser descargado

Precio 19,34 €

Comprar ahora
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
E-mail
Article options
Tools
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos

es en pt
Política de cookies Cookies policy Política de cookies
Utilizamos cookies propias y de terceros para mejorar nuestros servicios y mostrarle publicidad relacionada con sus preferencias mediante el análisis de sus hábitos de navegación. Si continua navegando, consideramos que acepta su uso. Puede cambiar la configuración u obtener más información aquí. To improve our services and products, we use "cookies" (own or third parties authorized) to show advertising related to client preferences through the analyses of navigation customer behavior. Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here. Utilizamos cookies próprios e de terceiros para melhorar nossos serviços e mostrar publicidade relacionada às suas preferências, analisando seus hábitos de navegação. Se continuar a navegar, consideramos que aceita o seu uso. Você pode alterar a configuração ou obter mais informações aqui.