Buscar en
Acta Otorrinolaringológica Española
Toda la web
Inicio Acta Otorrinolaringológica Española Hypoparathyroidism following thyroidectomy: Predictive factors
Journal Information
Vol. 68. Issue 2.
Pages 106-111 (March - April 2017)
Share
Share
Download PDF
More article options
ePub
Visits
829
Vol. 68. Issue 2.
Pages 106-111 (March - April 2017)
Original article
DOI: 10.1016/j.otoeng.2016.06.001
Hypoparathyroidism following thyroidectomy: Predictive factors
Hipoparatiroidismo tras tiroidectomía: factores predictivos
Visits
...
Cristiana Coimbra
Corresponding author
cfilipa.coimbra@gmail.com

Corresponding author.
, Francisco Monteiro, Pedro Oliveira, Leandro Ribeiro, Mário Giesteira de Almeida, Artur Condé
Centro Hospitalar Vila Nova de Gaia Espinho (CHVNGE), ENT Department, Gaia, Portugal
Article information
Abstract
Full Text
Bibliography
Download PDF
Statistics
Tables (3)
Table 1. Frequency of each surgery and its relation to the outcome of transient and permanent hypoparathyroidism.
Table 2. Histologic diagnosis of the specimen and its frequency related to the presence of transient and permanent hypoparathyridism.
Table 3. Thyroid's function before surgery ant its relation to the post surgery outcome of transient and permanent hypoparathyroidism.
Show moreShow less
Abstract
Objective

To evaluate the incidence and predictive factors for transient and permanent hypocalcemia and hypoparathyroidism following thyroidectomy.

Method

We studied all the 162 patients that underwent thyroid surgery in the ENT department of the Centro Hospitalar Vila Nova Gaia/Espinho from January 2005 to December 2014. We reviewed pre-operative, 6h and 12h after surgery ionized calcium and PTH levels. All patients were reviewed and evaluated according to the following criteria: gender, age, thyroid function, histologic diagnosis of the specimen, surgery extension and presence or absence of hypoparathyroidism.

Results

There were 31 (19.1%) cases of transient hypoparathyroidism and 8 (5%) of permanent hypoparathyroidism. No significant difference was found for transient hypoparathyroidism when patients were analyzed by gender. However, all cases of permanent hypoparathyroidism were observed in female individuals.

Comparing hemithyroidectomy with all other surgical procedures, we found that extension of surgery was a great predictor of transient (p=0.0001) and permanent (p=0.001) hypoparathyroidism.

Diagnosis of malignancy was a strong predictor of transient hypoparathyroidism (p=0.002). It was also associated with permanent hypoparathyroidism, although differences did not reach statistical significance (p=0.096).

Conclusion

Extension of surgery (total thyroidectomy) and diagnosis of malignancy are predictors of transient and permanent hypoparathyroidism.

Keywords:
Hypoparathyroidism
Predictive factors
Thyroidectomy
Hypocalcemia
Parathyroid gland
Histological diagnosis
Resumen
Objetivo

Evaluar la incidencia y los factores predictivos de hipocalcemia transitoria y permanente e hipoparatiroidismo tras la tiroidectomía.

Método

Se estudiaron todos los pacientes sometidos a cirugía de tiroides en el Servicio de ORL del Centro Hospitalario de Vila Nova de Gaia/Espinho desde enero de 2005 a diciembre de 2014. Se revisaron los valores de calcio ionizado preoperatorio, a las 6 y a las 12h de la intervención, y los niveles de PTH. Se revisaron y evaluaron todos los archivos de acuerdo con los siguientes criterios: sexo, edad, función tiroidea, diagnóstico histológico de la muestra, extensión de la cirugía y presencia o ausencia de hipoparatiroidismo.

Resultados

Encontramos 31 (19,1%) casos de hipoparatiroidismo transitorio y 8 (5%) de hipoparatiroidismo permanente. No se encontraron diferencias significativas en cuanto a hipoparatiroidismo transitorio cuando los pacientes fueron analizados por sexo. Sin embargo, todos los casos de hipoparatiroidismo permanente se observaron en individuos de sexo femenino. Comparando la hemitiroidectomía con el resto de los procedimientos quirúrgicos, se encontró que la extensión de la cirugía fue un gran factor predictivo de hipoparatiroidismo transitorio (p=0,0001) y permanente (p=0,001). El diagnóstico de malignidad es un fuerte factor predictivo de hipoparatiroidismo transitorio (p=0,002). También de hipoparatiroidismo permanente, aunque las diferencias no alcanzaron la significación estadística (p=0,096).

Conclusión

La extensión de la cirugía y el diagnóstico de malignidad son factores predictivos de hipoparatiroidismo transitorio y permanente.

Palabras clave:
Hipoparatiroidismo
Factores predictivos
Tiroidectomía
Hipocalcemia
Glándula paratiroidea
Diagnóstico histológico

Article

These are the options to access the full texts of the publication Acta Otorrinolaringológica Española
Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe
Subscribe to

Acta Otorrinolaringológica Española

Comprar
Comprar acceso al artículo

Comprando el artículo el PDF del mismo podrá ser descargado

Precio 22,50 €

Comprar ahora
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
E-mail
Article options
Tools
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos

es en pt
Política de cookies Cookies policy Política de cookies
Utilizamos cookies propias y de terceros para mejorar nuestros servicios y mostrarle publicidad relacionada con sus preferencias mediante el análisis de sus hábitos de navegación. Si continua navegando, consideramos que acepta su uso. Puede cambiar la configuración u obtener más información aquí. To improve our services and products, we use "cookies" (own or third parties authorized) to show advertising related to client preferences through the analyses of navigation customer behavior. Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here. Utilizamos cookies próprios e de terceiros para melhorar nossos serviços e mostrar publicidade relacionada às suas preferências, analisando seus hábitos de navegação. Se continuar a navegar, consideramos que aceita o seu uso. Você pode alterar a configuração ou obter mais informações aqui.