Buscar en
Revista Española de Cirugía Ortopédica y Traumatología
Toda la web
Inicio Revista Española de Cirugía Ortopédica y Traumatología [Translated article] Out-of-sheath corticosteroid injections through the dorsal ...
Información de la revista
Vol. 66. Núm. 4.
Páginas T260-T266 (Julio - Agosto 2022)
Compartir
Compartir
Descargar PDF
Más opciones de artículo
Visitas
121
Vol. 66. Núm. 4.
Páginas T260-T266 (Julio - Agosto 2022)
Original Paper
Open Access
[Translated article] Out-of-sheath corticosteroid injections through the dorsal webspace for trigger finger and trigger thumb. A prospective cohort study
Infiltración comisural dorsal en el tratamiento del pulgar y los dedos en resorte. Estudio de una cohorte prospectiva
Visitas
...
I. Jiméneza,b,
Autor para correspondencia
isidro_jimenez@hotmail.com

Corresponding author.
, J. Medinaa,b, A. Marcos-Garcíaa,b, G.L. Garcésb,c
a Servicio de Cirugía Ortopédica y Traumatología, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, Las Palmas, Spain
b Departamento de Ciencias Médicas y Quirúrgicas, Facultad de Medicina, Universidad de Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Las Palmas, Spain
c Servicio de Cirugía Ortopédica y Traumatología, Hospital Perpetuo Socorro, Las Palmas de Gran Canaria, Las Palmas, Spain
Contenido relaccionado
I. Jiménez, J. Medina, A. Marcos-García, G.L. Garcés
Información del artículo
Resumen
Texto completo
Bibliografía
Descargar PDF
Estadísticas
Figuras (3)
Mostrar másMostrar menos
Abstract
Background and objective

Steroid injections are effective in the treatment of trigger digits but the pain during the injection is an always-present accompanying effect. The aim of this study was to assess the effectiveness and perceived pain during an out-of-sheath corticosteroid injection through the dorsal webspace in the treatment of trigger digits.

Material and method

A total of 126 consecutive patients were included. A subcutaneous (out-of-sheath) corticosteroid injection was performed through the dorsal webspace in all digits. In cases where signs or symptoms persisted, a second injection was offered. Visual analog scale for pain during the injection, DASH questionnaire, success rate and complications were collected.

Results

They were 86 women and 40 men with a mean age of 61 years. The mean VAS for pain during the injection was 3.8. Twelve patients were lost to follow-up. The overall success was 68% and success after a single injection was 54%. The best result was achieved on the ring finger. Patients who were not previously operated on carpal tunnel syndrome responded better. No complications were noted.

Conclusions

The extra-sheath corticosteroid injection through the dorsal webspace is effective and safe. It seems to be less painful than the reported scores for the palmar midline technique although it should be assessed in a comparative study.

Keywords:
Injection
Pain
Trigger finger
Trigger thumb
Webspace
Flexor tendon
Resumen
Antecedentes y objetivo

Las infiltraciones de corticoides son efectivas en el tratamiento de los dedos en gatillo, pero el dolor percibido por el paciente durante la inyección es un efecto acompañante siempre presente. El objetivo de este estudio fue evaluar la efectividad y el dolor percibido durante una infiltración corticoidea depositada fuera de la vaina tendinosa utilizando la técnica comisural dorsal.

Material y método

Se incluyeron 126 pacientes consecutivos. Se realizó una infiltración esteroidea subcutánea (fuera de la vaina) a través de la comisura dorsal. En los casos en que los signos o síntomas persistieron, se ofreció una segunda infiltración. Se registró el dolor percibido durante la infiltración mediante la escala visual analógica, el cuestionario DASH antes del tratamiento y al final de seguimiento, la tasa de éxito y las complicaciones.

Resultados

Fueron 86 mujeres y 40 varones con una edad media de 61 años. La puntuación media del dolor durante la infiltración fue de 3,8. Doce pacientes se perdieron durante el seguimiento. El éxito global fue del 68% y el éxito tras una única inyección fue del 54%. El mejor resultado se obtuvo en el dedo anular. Los pacientes que no habían sido operados previamente del síndrome del túnel carpiano respondieron mejor. No se objetivaron complicaciones.

Conclusiones

La infiltración esteroidea fuera de la vaina tendinosa y utilizando la técnica comisural dorsal es efectiva y segura en el tratamiento de los dedos en resorte. Parece ser menos dolorosa que los resultados publicados para la técnica palmar sobre la línea media, aunque esto debe evaluarse en un estudio diseñado para ello.

Palabras clave:
Infiltración
Dolor
Dedo en resorte
Pulgar en resorte
Comisura
Tendón flexor
Texto completo
Introduction

Stenosing tenosynovitis, trigger finger or spring finger is one of the most common causes of hand pain and disability, affecting 2.6% of non-diabetic adults and up to 10% of the diabetic population.1,2 The goal of treatment is to restore smooth, painless gliding of the tendons and full range of motion in the affected finger.

Trigger fingers can be effectively and efficiently treated by steroid injections,3–8 but pain experienced by the patient is an ever-present side effect. Few studies have assessed patient-perceived pain during trigger finger injections, but the score seems to vary depending on the injection technique.9–13

The palmar technique over the midline and depositing the injection into the tendon sheath is probably the most commonly used technique, but others have been described, such as the distal palmar technique, the mid-axial technique or an intra-vain technique through the dorsal webspace.1,8–10,14

The volar region of the hand is more innervated than the dorsal region and therefore injection through the dorsum may theoretically be less painful than injection through the palm. This claim has recently been questioned in some studies conducted to evaluate the least painful method of performing a digital block, in which volunteers prefer a single injection through the palm rather than 2 through the dorsum. In the treatment of trigger fingers, only one dorsal injection would be performed and not 2, so the best technique for injection remains a controversial issue.6,9,15–19

Injection within the tendon sheath has been associated with an increase in perceived pain compared to a subcutaneous technique.20 Some studies have shown that subcutaneous palmar injection is as effective as the intra-sheath technique, reducing the risk of flexor tendon and pulley injury; therefore, depositing the injection within the tendon sheath appears to be unnecessary.1,21,22

The aim of this study was to evaluate the effectiveness and perceived pain during subcutaneous corticosteroid injection using the dorsal commissural technique in the treatment of trigger fingers.

Material and methodStudy population and design

Following approval by the clinical research committee of our centre (CEIC-CHUIMI-2015/789) and after evaluating the safety and potential efficacy of the dorsal web space technique,23 all patients diagnosed with spring finger by one of 3 orthopaedic surgeons and traumatologists during a one-year period were invited to participate in this prospective cohort study (Fig. 1). Written informed consent was obtained from all subjects prior to the study. All procedures followed conformed to the ethical standards of the committee responsible for human experimentation (institutional and national) and to the Helsinki Declaration of 1975, revised in 2008.

Figure 1.

Flow diagram of the study.

(0,39MB).

The diagnosis was made based on the patient's symptoms and signs, such as painful springing or locking of the involved finger when the patient flexes and extends it.

Inclusion criteria: any adult patient diagnosed with trigger finger who agreed to participate. Exclusion criteria: (1) involvement of more than one finger; (2) contraindication for treatment according to the product package insert, such as known allergy to the injection components or uncontrolled diabetes mellitus (glycosylated haemoglobin>8%); (3) inflammatory or autoimmune arthritis; (4) previous injection or surgery on the affected finger; and (5) pregnancy or breastfeeding.

The minimum follow-up was 12 months.

Injection technique

In all cases a 2ml syringe loaded with 1ml betamethasone 6mg/1ml (Celestone Cronodose®, Merck Sharp & Dohme Laboratories, Spain) and 1ml mepivacaine 2% (Normon Laboratories, Spain) was used. Puncture was performed using a 25G needle (SurGuard2, Terumo®, Terumo Medical Corporation, USA).

In the thumb, a dorsal-ulnar injection was performed at the level of the metacarpophalangeal joint, keeping the thumb in maximum abduction and directing the needle into the subcutaneous cellular tissue at the level of the head of the first metacarpal at a 90° angle to the axis of the thumb (Fig. 2).

Figure 2.

Dorsal-ulnar injection performed on the thumb at the level of the metacarpophalangeal joint keeping the thumb in maximum abduction, directing the needle towards the subcutaneous cellular tissue at the level of the head of the first metacarpal at an angle of 90 with respect to the axis of the thumb.

(0,15MB).

In the long fingers, the puncture was performed keeping the metacarpophalangeal joint slightly flexed (approximately 30) and directing the needle into the subcutaneous cellular tissue at the level of the metacarpal head at an angle of 45 with respect to the axis of the finger (Fig. 3). In the index finger, a dorsal-ulnar injection was performed (through the second web space). The technique was not performed through the first web space because it is wider and deeper, which, in our experience, makes it difficult to guide the needle. In the middle and ring fingers, dorsoradial or dorsal-ulnar injection was performed according to the investigator's preference. Finally, the little finger was infiltrated dorsoradially.

Figure 3.

Dorsal web space injection performed on the index finger keeping the metacarpophalangeal joint slightly flexed and directing the needle towards the metacarpal head at an angle of 45 with respect to the axis of the metacarpal.

(0,27MB).

The location of the needle tip outside the tendon sheath was confirmed by asking the patient to slightly flex the finger after inserting the needle and verifying that the needle did not move with flexor tendon movement.

All patients were reviewed in the clinic at 1 month, 3 months and 12 months. Those patients in whom signs or symptoms persisted at the 1-month or 3-month visit were offered a second injection.

Tools and measurements

Demographics; comorbidities; time from symptom onset to diagnosis; Green's classification (Table 1)1; Disabilities of the Arm, Shoulder and Hand (DASH; 0–100 points) before injection and at final follow-up24; pain during injection measured by visual analogue scale (VAS; 0–10 points); number of injections; success rate and complications were recorded. During and after injection, patients were specifically asked about the presence of paraesthesia or numbness of the finger.

Table 1.

Green's classification for trigger fingers.

Grade  Clinical findings 
Pain on pulley A1 
II  Trigger. The patient can actively extend the finger 
III  Blocked. The patient passively extends the finger. 
IV  Fixed stiffness in flexion 
Source: Wolfe.1

Success was defined as complete resolution of symptoms with no recurrence of pain or trigger finger during the 12 months of follow-up.

Recurrence was defined as the appearance of symptoms (pain) or signs (trigger or block) after an asymptomatic period of at least one month.

Pain score was measured after injection in an adjoining room using a 10cm line (from 0=no pain to 10=the worst pain experienced), where patients marked a score.

Statistical analysis

All data were analysed using Microsoft Excel 2011 (version 14.6.0, 2010; Microsoft Corporation, USA), StatPlus: mac (version V6 2016; AnalystSoft Inc., USA) and MatLab (version R2019a; The MathWorks Inc., USA). Statistical analysis of the data was performed using Student's t-test for paired samples, the Chi-square test and Fisher's exact test. A value of p<.05 was considered statistically significant.

Results

One hundred and twenty six of the 141 consecutive patients were included. Demographic characteristics of the patients and the distribution according to the affected finger are shown in Table 2.

Table 2.

Demographic data and digital distribution.

Age (years), mean (range)  61 (42–82) 
Sex, n
Woman  86 
Man  40 
Diabetes mellitus, n (%)
Yes  14 (11) 
No  112 (89) 
Previous carpal tunnel surgery, n (%)
Yes  18 (14) 
No  108 (86) 
Time since onset of symptoms (months), mean (range)  7 (1–24) 
Affected finger, n (%)
Thumb  38 (30) 
Index  12 (10) 
Middle finger  48 (38) 
Ring finger  24 (19) 
Little finger  4 (3) 
Grade according to Green, n
II  28 
III  86 
IV 

The mean VAS score for pain during injection was 3.8 points (range 0–10; standard deviation [SD]: 2.3; 95% confidence interval [95% CI95%]: 3.4–4.2) and was considered as no pain (VAS for pain=0) in 4 patients; mild pain (VAS for pain=1–4) in 78, moderate pain (VAS for pain=5–7) in 36 patients and severe pain (VAS for pain=8–10) in 8 cases. These categories were arbitrarily created to stratify patients.

We found no statistically significant differences in the VAS score for pain according to the affected finger.

The mean DASH questionnaire score at diagnosis was 48 points (range 0–91; SD: 25; 95% CI: 44–52). The mean DASH questionnaire score at the end of follow-up was 8.6 points (range 0–50; SD: 16; 95% CI: 5.8–11) (p<.05).

Twelve patients were lost to follow-up. In the 114 patients available at the end of follow-up, the overall success rate was 78/114 (68%).

The success rate after one injection was 62/114 (54%). Twenty-eight patients refused a second injection and were referred to surgery. The success rate of the second injection was 16/24 (66%).

Success rates according to affected finger and according to Green's classification are shown in Table 3.

Table 3.

Success rate according to the affected finger and Green's classification.

Affected finger  n  Resolved  Unresolved 
Thumb  34  18  16  53 
Index  25 
Middle  44  37  81 
Ring  24  20  83 
Little  33 
Green's grade  n  Resolved  Unresolved 
100 
II  24  18  75 
III  78  49  29  63 
IV  83 
Total  114  78  36  68 

There were 4 recurrences between the 3-month and 12-month review which were considered and analysed as treatment failures.

No neurological or other complications were observed.

We found no statistically significant difference in success rate between the diabetic and non-diabetic population (10/12 and 68/102, respectively; p=.33).

There was a statistically significant difference in the success rate between patients who had previously undergone surgery for carpal tunnel syndrome and those who had not (8/18 and 70/96, respectively; p<.05).

Discussion

The results obtained in this cohort study support the use of steroid injection deposited outside the tendon sheath and performed using the dorsal commissural technique in the treatment of trigger fingers as an effective, safe and potentially less painful technique.

Corticosteroid injection is a useful and safe treatment in stenosing tenosynovitis of the flexor tendons1,3,7 but pain perceived during injection is always present. Among the different injection techniques described, using the medioaxial technique, a mean pain score of 4 has been published; using the palmar over midline technique, 5.4 (ranging from 3.3 to 6.6); using the distal palmar technique, 6 (only in 12 fingers), and finally, using the dorsal intra-axial technique, the mean VAS score was 6.8 (only in 5 fingers) (Table 4).9–13 In our series, using a dorsal commissural extra-valvular technique, the mean VAS score was 3.8.

Table 4.

Published pain score for the different techniques described.

Author (year)  Technique  Cases  Mean score for VAS pain (0–10) 
Jianmongkol et al. (2007)9Mid-axial  53  4.0 
Palmar mid-line  48  4.8 
Park et al. (2014)12Palmar mid-line  30  5.6 
Palmar mid-line+vibration  30  5.6 
Palmar mid-line +false vibration  30  6.3 
Earp et al. (2017)11,aRosenbaum et al. (2018)10Palmar mid-line  29  4.6 
Palmar distal  12  6.0 
Palmar mid-line  22  6.6 
Dorsal intra-sheath  6.8 
Patel et al. (2019)13,a  Palmar mid-line  15  4.9 
Our series  Dorsal out-of-sheath web space  126  3.8 
a

In order to compare only the perceived pain associated with the injection itself, the groups of patients in which non-injected local anaesthesia was used prior to the puncture have been removed from the table.

In our study population, resolution of symptoms was obtained after a single injection in 54% of cases, a result similar to previously published data for other techniques, which range from 44% to 66%. The overall success rate at the end of follow-up was 68%, also similar to previously published results using the palmar midline technique.2–7,25

In our cohort, we found no differences in the success rate between the diabetic and non-diabetic population, in contrast to what has been previously published in other studies.3,26,27 We considered and analysed as diabetic those patients who reported being diabetic, but the rest of the patients did not undergo blood glucose testing. This may have underestimated the number of diabetic patients in the sample and should therefore be considered a limitation of the study.

In our study population, patients who had not previously undergone surgery for carpal tunnel syndrome responded better to injection. In vitro and in vivo studies have shown that the flexor tendons are displaced palmarly after opening of the transverse carpal ligament and this modifies the angle of entry of the flexor tendons into the A1 pulley, leading to increased friction.28,29 Our results could be explained by the fact that this increased friction between the flexor tendons and the pulley entry would be more difficult to counteract by the anti-inflammatory effect of corticosteroids.

We observed a significant decrease in the score on the DASH questionnaire, although the final score was not zero, as would be expected after resolution of the condition. This result should be interpreted with caution, as other factors may influence the score on self-perceived questionnaires and disability questionnaires. This observation is in line with other studies showing that the DASH questionnaire score is largely determined by psychosocial factors that may not change even if the objective disease state under study does.30

The strengths of our work are: the functional status of the patients was assessed prospectively before and after treatment. The rate of follow-up loss was under 10%.

This study has limitations. Assuming that the needle tip was located outside the tendon sheath due to the absence of movement of the needle during flexion-extension of the finger could lead to an error, as strictly speaking, this method would only confirm that the needle tip was not inserted into the flexor tendon. The use of ultrasound could have been helpful in this respect. This is a prospective, non-comparative cohort and therefore lacks a control group. The sample size was small and this may have influenced the results of the subgroup analysis.

According to the results of this cohort, steroid injection deposited outside the tendon sheath and performed using the dorsal commissural technique in the treatment of trigger fingers is effective and safe. This technique appears to be less painful and at least as effective as previously published results using the palmar midline technique, although this aspect needs to be evaluated in a comparative study designed for this purpose.

Level of evidence

Level of evidence ii.

Authors’ contribution

IJ and JM conceived the study, conducted the literature search and wrote the first draft of the manuscript. IJ, GG and AMG were involved in protocol development and obtaining ethical approval. IJ, AMG and JM participated in patient selection. IJ and GG were involved in data analysis. All authors reviewed and edited the manuscript and approved the final version of the manuscript.

Financing

This research was partially funded by the Foundation of the Colegio Oficial de Médicos de Las Palmas (Grant: XXIV, 2019 I+E Grand Edition).

Conflict of interests

The authors have no possible conflict of interests to declare with respect to the research, authorship and/or publication of this paper.

Acknowledgements

Our thanks to A. Samuel A. Jiménez, BEng., MSc, for their help with the statistical analysis of this investigation.

References
[1]
S.W. Wolfe.
Tendinopathy.
Green's operative hand surgery, 6th ed., pp. 2064-2188
[2]
M. Ryzewicz, J. Wolf.
Trigger digits: principles, management, and complications.
J Hand Surg Am, 31A (2006), pp. 135-146
[3]
J. Castellano, E. Muñoz-Mahamud, E. Domínguez, P. Del Amo, O. Izquierdo, P. Fillat.
Long-term effectiveness of corticosteroid injections for trigger finger and thumb.
J Hand Surg Am, 40 (2015), pp. 121-126
[4]
B.M. Dala-Ali, A. Nakhdjevani, M.A. Lloyd, F.V. Schreuder.
The efficacy of steroid injection in the treatment of trigger finger.
Clin Orthop, 4 (2012), pp. 263-268
[5]
A. Mathew.
Mid-axial injection of steroid into the flexor sheath for trigger fingers.
J Hand Microsurg, 6 (2014), pp. 49-52
[6]
D. Murphy, J.M. Failla, M.P. Koniuch.
Steroid versus placebo injection for trigger finger.
J Hand Surg Am, 20 (1995), pp. 628-631
[7]
A. Halim, A.D. Sobel, A.E.M. Eltorai, K.P. Mansuripur, A.C. Weiss.
Cost-effective management of stenosing tenosynovitis.
J Hand Surg Am, 43 (2018), pp. 1085-1091
[8]
C.S. Carlson, R.M. Curtis.
Treatment of flexor tenosynovitis.
J Hand Surg Am, 9 (1984), pp. 286-288
[9]
S. Jianmongkol, W. Kosuwon, T. Thammaroj.
Intra-tendon sheath injection for trigger finger: the randomized controlled trial.
Hand Surg, 12 (2007), pp. 79-82
[10]
Y.A. Rosenbaum, N. Benvenuti, J. Yang, M.E. Ruff, H.M. Awan, J.B. Samora.
The effect of trigger finger injection site on injection-related pain.
Hand (N Y), 13 (2018), pp. 164-169
[11]
B.E. Earp, S.J. Stanbury, A.N. Mora, P.E. Blazar.
Needle-free jet lidocaine administration for preinjection anesthesia in trigger finger injection: a randomized controlled trial.
J Hand Surg Am, 42 (2017), pp. 618-622
[12]
K.W. Park, M.I. Boyer, R.P. Calfee, C.A. Goldfarb, D.A. Osei.
The efficacy of 95-Hz topical vibration in pain reduction for trigger finger injection: a placebo-controlled, prospective, randomized trial.
J Hand Surg Am, 39 (2014), pp. 2203-2207
[13]
K.R. Patel, D. Fralinger, K.J. MacGillis, J. Wright-Chisem, A. Mejia.
The anesthetic effectiveness of j-tip needle-free injection system prior to trigger finger injection: a double-blind randomized clinical trial.
Hand (N Y), 3 (2019),
[14]
N. Buch-Jaeger, G. Foucher, S. Ehrler, D. Sammut.
The results of conservative management of trigger finger.
Ann Hand Surg, 11 (1992), pp. 189-193
[15]
L. Fisher, M. Gordon.
Anesthesia for hand surgery.
Green's operative hand surgery, 6th ed., pp. 25-40
[16]
M.F. Nolan.
Two-point discrimination assessment in the upper limb in young adult men and women.
Phys Ther, 62 (1982), pp. 965-969
[17]
J.P. Koo, S.H. Kim, H.J. An, et al.
Two-point discrimination of the upper extremities of healthy Koreans in their 20's.
J Phys Ther Sci, 28 (2016), pp. 870-874
[18]
J.G. Williams, D.H. Lalonde.
Randomized comparison of the single-injection volar subcutaneous block and the two-injection dorsal block for digital anesthesia.
Plast Reconstr Surg, 118 (2006), pp. 1195-1200
[19]
M.E. Wheelock, M. Leblanc, B. Chung, J. Williams, D.H. Lalonde.
Is it true that injecting palmar finger skin hurts more than dorsal skin? New level 1 evidence.
Hand (N Y), 6 (2011), pp. 47-49
[20]
Z.G. Yin, J.B. Zhang, S.L. Kan, P. Wang.
A comparison of traditional digital blocks and single subcutaneous palmar injection blocks at the base of the finger and a meta-analysis of the digital block trials.
J Hand Surg Br, 31 (2006), pp. 547-555
[21]
J.S. Taras, J.S. Raphael, W.T. Pan, F. Movagharnia, D.G. Sotereanos.
Corticosteroid injections for trigger digits: is intrasheath injection necessary?.
J Hand Surg Am, 23 (1998), pp. 717-722
[22]
K. Kazuki, T. Egi, M. Okada, et al.
Clinical outcome of extrasynovial steroid injection for trigger finger.
[23]
I. Jiménez, G.L. Garcés, J. Caballero-Martel, J. Medina.
Dorsal web space injection technique in the treatment of trigger fingers and trigger thumb. Anatomical study.
Rev Esp Cir Ortop Traumatol, 64 (2020), pp. 355-360
[24]
R.S. Rosales, E.B. Delgado, I. Díez de Lastra-Bosch.
Evaluation of the Spanish version of the DASH and carpal tunnel syndrome health-related quality-of-life instruments: cross-cultural adaptation process and reliability.
J Hand Surg Am, 27 (2002), pp. 334-343
[25]
R.D. Wojan, N.C. Foeger, R.H. Gebelman, R.P. Calfee.
Long-term outcomes following a single corticosteroid injection for trigger finger.
J Bone Joint Surg Am, 96 (2014), pp. 1849-1854
[26]
S.M. Griggs, A.P. Weiss, L.B. Lane, C. Schewenker, E. Akelman, K. Sachar.
Treatment of trigger finger in patients with diabetes mellitus.
J Hand Surg Am, 20 (1995), pp. 787-789
[27]
K.M. Baumgarten, D. Gerlach, M.I. Boyer.
Corticosteroid injection in diabetic patients with trigger finger: a prospective, randomized, controlled double-blinded study.
J Bone Joint Surg, 89 (2007), pp. 2604-2611
[28]
N. Karalezli, H. Kütahya, A. Güle, S. Toker, H. Karabörk, T.C. Ogun.
Transverse carpal ligament and forearm fascia release for the treatment of carpal tunnel syndrome change the entrance angle of flexor tendons to the A1 pulley: the relationship between carpal tunnel surgery and trigger finger occurrence.
Sci World J, 2013 (2013), pp. 630-717
[29]
S.K. Lee, K.W. Bae, W.S. Choy.
The relationship of trigger finger and flexor tendon volar migration after carpal tunnel release.
J Hand Surg Eur Vol, 39 (2014), pp. 694-698
[30]
D. Ring, S. Lozano-Calderón, R. Shin, P. Bastian, C. Mudgal, J. Jupiter.
A prospective randomized controlled trial of injection of dexamethasone versus triamcinolone for idiopathic trigger finger.
J Hand Surg Am, 33 (2008), pp. 516-522

The preliminary results of this study were presented orally at the annual congress of the French Hand Surgery Society in 2019, the abstract of which was published in their journal (Hand Surg Rehabil. 2019;38:419. doi:10.1016/j.hansur.2019.10.079).

Copyright © 2021. SECOT
Opciones de artículo
Herramientas
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos