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Inicio Revista Chilena de Pediatría The appropriate age to study the incidence of Helicobacter pylori infection
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Vol. 87. Núm. 6.
Páginas 513 (Noviembre - Diciembre 2016)
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Vol. 87. Núm. 6.
Páginas 513 (Noviembre - Diciembre 2016)
Letter to the Editor
DOI: 10.1016/j.rchipe.2016.07.013
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The appropriate age to study the incidence of Helicobacter pylori infection
La edad adecuada para el estudio de la incidencia de la infección por Helicobacter pylori
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Rinaldo Pellicano
Unit of Gastroenterology and Hepatology, Molinette Hospital, Turin, Italy
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Dear Editor,

I have read with great interest the study by Troncoso et al., showing that in Santiago, Chile, despite having a significant percentage of Helicobacter pylori (H. pylori)-infected mothers (40%), no newborn was infected at the third month of life.1 It is known that H. pylori infection is acquired in the preschool age group, with the associated effects of family size, clustering in families, high infection rate accompanying low socioeconomic status and education,2 and that the risk declines rapidly after 5 years of age.3 The striking results obtained by Troncoso et al. add another piece of knowledge establishing that such risk increases in the period between 3 months and 5 years. These crucial data can lead to explain in depth both the true age of H. pylori infection and the possible mode of transmission of the organism. In fact, a consequence of this study is the possibility to devise intervention strategies to prevent the infection, especially in country with high rate of gastric benign and malignant diseases caused by the bacterium.4 This is more evident considering the therapeutic difficulties due to the increasing rates of H. pylori-resistance to antimicrobials.5

Ethical disclosuresProtection of human and animal subjects

The authors declare that no experiments were performed on humans or animals for this study.

Confidentiality of data

The authors declare that no patient data appear in this article.

Right to privacy and informed consent

The authors declare that no patient data appear in this article.

References
[1]
P. Troncoso, A. Villagràn, M. Vera, et al.
La infección materna por Helicobacter pylori no aumenta el riesgo de contraer la bacteria en el primer trimestre de vida de sus lactantes.
Rev Chil Pediatr, 26 (2016), pp. 513-516
[2]
G. Oderda, M. Marietti, R. Pellicano.
Diagnosis and treatment of Helicobacter pylori infection in pediatrics: recommendation for 2014 clinical practice.
Minerva Pediatr, 67 (2015), pp. 517-524
[3]
M. Rowland, L. Daly, M. Vaughan, A. Higgins, B. Bourke, B. Drumm.
Age-specific incidence of Helicobacter pylori.
Gastroenterology, 130 (2006), pp. 65-72
[4]
P. Malfertheiner, F. Mégraud, C. O’Morain, et al.
Management of Helicobacter pylori infection: the Maastricht IV/Florence Consensus Report.
[5]
A. Tursi, W. Elisei, G. Giorgetti, M. Picchio, G. Brandimarte.
Decreasing efficacy of the standard seven-day triple therapy containing amoxycillin and clarithromycin in curing Helicobacter pylori infection in clinical setting in Italy: a 10-year follow-up study.
Panminerva Med, 56 (2014), pp. 57-61
Copyright © 2016. Sociedad Chilena de Pediatría
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