Información del artículo
La neuropatía es una complicación frecuente de la diabetes mellitus. Un porcentaje significativo de los pacientes con neuropatía diabética presenta dolor neuropático crónico con impacto en el paciente y su calidad de vida. La pregabalina es un fármaco con actividad antiepiléptica, analgésica y ansiolítica del que se ha demostrado utilidad en el tratamiento del dolor neuropático periférico. En el presente artículo se revisan sus propiedades farmacológicas y la evidencia científica que justifica la utilidad de la pregabalina en el tratamiento de la neuropatía diabética dolorosa.
Palabras clave:
Pregabalina
Neuropatía diabética
Dolor neuropático
Neuropathy is a frequent complication of diabetes mellitus. A substantial percentage of patients with diabetic polyneuropathy report chronic neuropathic pain with significant impairment of quality of life. Pregabalin is a drug with antiepileptic, analgesic and anxiolytic activity, which has been demonstrated to be useful in the treatment of peripheral neuropathic pain. The present article reviews the pharmacological profile and scientific evidence that justifies the use of this drug in painful diabetic polyneuropathy.
Key words:
Pregabalin
Diabetic neuropathy
Neuropathic pain
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