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Inicio Archivos de la Sociedad Española de Oftalmología (English Edition) Stenotrophomonas maltophilia keratitis treated with trimethoprim–sulfamethoxaz...
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Vol. 90. Issue 11.
Pages 539-541 (November 2015)
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Vol. 90. Issue 11.
Pages 539-541 (November 2015)
Short communication
Stenotrophomonas maltophilia keratitis treated with trimethoprim–sulfamethoxazole
Queratitis por Stenotrophomonas maltophilia tratada con trimetoprima-sulfametoxazol
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L. Díez-Álvareza,
Corresponding author
diezalvarezl@gmail.com

Corresponding author.
, B. Lumbreras-Fernándeza, J.L. García-Péreza,b
a Servicio de Oftalmología, Hospital Universitario Ramón y Cajal, Madrid, Spain
b Clínica Rementería, Madrid, Spain
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Abstract
Case report

An 84-year-old woman presented with persistent epithelial defect and a dense stromal infiltrate post-corneal transplantation. According to the microbiological results, it was due to a Stenotrophomonas maltophilia (S. maltophilia) resistant to all antibiotics except trimethoprim–sulfamethoxazole (TMP/SMX). Healing was achieved after three weeks of treatment with oral and topical TMP/SMX.

Discussion

S. maltophilia is an opportunistic microorganism rarely described in ophthalmology. It is associated with conjunctivitis, keratitis, scleritis, dacryocystitis, cellulitis, and endophthalmitis with significant morbidity. Treatment is complicated because of its resistances to broad-spectrum antibiotics. TMP/SMX monotherapy can be considered an option of treatment for this type of keratitis.

Keywords:
Stenotrophomonas maltophilia
Keratitis
Cornea
Ciprofloxacin
Trimethoprim–sulfamethoxazole
Resumen
Caso clínico

Mujer de 84 años con defecto epitelial persistente e infiltrado estromal denso tras trasplante corneal. El análisis microbiológico reveló una Stenotrophomonas maltophilia (S. maltophilia), resistente a todos los antibióticos salvo a trimetoprima-sulfametoxazol (TMP/SMX) Se consiguió su resolución tras 3 semanas de tratamiento con TMP/SMX tópico y oral.

Discusión

S. maltophilia es un microorganismo oportunista raramente descrito en oftalmología. Se asocia con conjuntivitis, queratitis, escleritis, dacriocistitis, celulitis y endoftalmitis, con importante morbilidad. El tratamiento es complicado por sus múltiples resistencias a antibióticos de amplio espectro. El TMP/SMX en monoterapia puede considerarse como una opción de tratamiento para estas queratitis.

Palabras clave:
Stenotrophomonas maltophilia
Queratitis
Córnea
Ciprofloxacino
Trimetoprima-sulfametoxazol

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