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Inicio Archivos de la Sociedad Española de Oftalmología (English Edition) Combined intrastromal injection of ganciclovir and depot betamethasone for the m...
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Vol. 94. Issue 7.
Pages 347-351 (July 2019)
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Vol. 94. Issue 7.
Pages 347-351 (July 2019)
Short communication
Combined intrastromal injection of ganciclovir and depot betamethasone for the management of nummular keratitis: Case series
Inyección intraestromal combinada con ganciclovir y betametasona de depósito para el manejo de la queratitis numular: serie de casos
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E. Arenasa, A. Miethb, D. Muñoza,c,
Corresponding author
diannymsm@gmail.com

Corresponding author.
a Sociedad de Oftalmología Eduardo Arenas Archila, Bogotá, Colombia
b Asociación Colombiana de Córnea y Cirugía Refractiva (ASOCORNEA), Bogotá, Colombia
c Universidad Nacional de Colombia, Bogotá, Colombia
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Table 1. Eyes included in the case series.
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Abstract

Nummular keratitis is an inflammatory process of the cornea that is characterized by multiple sub-epithelial deposits, for which a variety of therapeutic approaches have been proposed. A retrospective review was performed using the medical records of patients diagnosed with nummular keratitis and treated with a combined intrastromal injection of ganciclovir and depot betamethasone between the years 2009 and 2017. A total of 21 eyes of 16 patients were finally included. Upon termination of the treatment, 18 eyes (85.71%) were asymptomatic. This improvement was maintained during a mean follow-up time of 22.90 months. Depot betamethasone mixed with ganciclovir by intrastromal application is a good alternative for the treatment of nummular keratitis.

Keywords:
Cornea
Nummular keratitis
Ganciclovir
Betamethasone
Resumen

La queratitis numular es un proceso inflamatorio de la córnea que se caracteriza por múltiples depósitos subepiteliales y para la cual se han propuesto diversas aproximaciones terapéuticas. Se realizó una revisión retrospectiva de las historias clínicas de pacientes diagnosticados con queratitis numular entre los años 2009 y 2017, que incluyó 21 ojos de 16 pacientes tratados con una inyección intraestromal combinada de ganciclovir y betametasona de depósito. Al finalizar el tratamiento, 18 ojos (85,71%) estaban asintomáticos. Esta mejora se mantuvo durante un tiempo medio de seguimiento de 22,90 meses. La combinación de betametasona de depósito mezclada con ganciclovir mediante aplicación intraestromal es una buena alternativa para el tratamiento de la queratitis numular.

Palabras clave:
Córnea
Queratitis numular
Ganciclovir
Betametasona

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