Choroidal neovascularization secondary to angioid streaks: A familial case report

Abstract

Case report

We report a familial case of 2 siblings that suffered choroidal neovascularization (CNV) secondary to angioid streaks. They were both treated with a monthly intravitreal injection of ranibizumab (Lucentis^®) for 3 months. Visual acuity was stabilized and fluorescein angiography revealed complete resolution of CNV. Neither recurrent CNV lesion nor new hemorrhages were reported during the follow-up period.

Discussion

The use of intravitreal ranibizumab for the treatment of CNV in patients with angioid streaks has shown favorable results. However, further studies with a longer follow-up and larger number of patients are necessary to more precisely determine the results of this therapy.

Resumen

Caso clínico

Se expone el caso de dos hermanos que presentaron neovascularización coroidea asociada a estrías angioides. Ambos pacientes fueron tratados con una inyección mensual de ranibizumab (Lucentis^®) intravítrea durante tres meses. La visión se estabilizó y la angiografía fluoresceínica mostró resolución completa de la neovascularización coroidea. Durante el seguimiento, no observamos recurrencia del cuadro.

Discusión

El uso de ranibizumab intravítreo en caso de neovascularización coroidea asociada a estrías angioides ha mostrado resultados favorables. No obstante, serán necesarias series de casos mayores que nos permitan conocer la verdadera eficacia de este tratamiento.