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Vol. 54. Núm. 3.
Páginas 162-173 (Enero 2002)
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Vol. 54. Núm. 3.
Páginas 162-173 (Enero 2002)
Acceso a texto completo
Tratamiento médico de la claudicación intermitente
The medical treatment of intermittent claudication
Tratamento médico da claudicação intermitente
Visitas
6690
C. Corominas-Roura
Autor para correspondencia
croura@hsd.es

correspondence: Monti-Sion, 18.E.07001 Palma de Mallorca, Illes Balears
, A. Plaza-Martínez, M. Díaz López, R. Riera-Vázquez, J. Cordobés-Gual
Servicio de Angiología y Cirugía Vascular. Hospital Universitari Son Dureta. Palma de Mallorca, Illes Balears, España.
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Información del artículo
Resumen
Bibliografía
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Estadísticas
Summary
Introduction

The diagnosis of intermittent claudication due to arteriosclerosis of the arteries of the lower limbs implies a significant increase in the risk of cardiovascular complications (CVC) and markedly reduced quality of life.

Objective

To consider the modification of risk factors for the progression of arteriosclerosis as the main factor in treatment.

Conclusions

Aspirin is the drug offirst choice in the secondary prevention of CVC in patients with peripheral arterial disease, and clopidogrel, which is potentially the most effective, is an alternative treatment for patients with chronic ischaemia of the lower limbs. The currently available data is not sufficient to be able to recommend the systematic use of a specific drug in all patients with claudication.

Key words:
Arteriosclerosis
Aspirin
Chronic ischaemia
Clopidogrel
Intermittent claudication
Lower limbs
Resumen
Introducción

El diagnóstico de claudicación intermitente por afectación arteriosclerótica de las arterias de las extremi dades inferiores (EEII) implica un incremento significativo del riesgo de complicaciones cardiovasculares (CCV), así como una limitación importante de la calidad de vida.

Objetivo

Considerar la modificación de los factores de riesgo de progresión de la arteriosclerosis como factor prioritario de trata miento.

Conclusiones

La aspirina constitu ye el fármaco de primera elección en la prevención secundaria de las CCV en pacientes con enfermedad arterial periférica, y elclopidogrel, con efecto potencialmente más eficaz, representa una alternativa en pacientes con isquemia crónica de las EEII. Los datos actuales son insuficientes para recomendar el uso sistemático de un fármaco específico en todos los pacientes con claudicación.

Palabras clave:
Arteriosclerosis
Aspirina
Claudicación intermitente
Clopidogrel
Extremidades inferiores
Isquemia crónica
Resumo
Introdução

O diagnóstico da claudicação intermitente por envolvimento arteriosclerótico das artérias dos membros inferiores (MI) implica um incremento significativo do risco das complicações cardiovasculares (CCV), bem como uma limitação importante da qualidade de vida.

Objectivo

Considerar a modificação dos factores de risco da progressão da arteriosclerose como factor prioritário de tratamento.

Conclusões

A aspirina constitui o fármaco de primeira escolha na prevenção secundária das CCV em doentes com doença arterial periférica, e o clopidogrel, com efeito potencialmente mais eficaz, representa uma alternativa em doentes com isquemia crónica dos MI. Os dados actuais são insuficientes para recomendar a utilização sistemáti ca de um fármaco específico em todos os doentes com claudicação.

Palavras clave:
Arteriosclerose
Aspirina
Claudicação intermitente
Clopidogrel
Membros inferiores
Isquemia crónica
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Bibliografía
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[3.]
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Diagnosis and treatment of chronic arterial insufficiency of the lower extremities: a critical review.
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J Vasc Surg., (2000), pp. 31
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J Vasc Surg., 30 (1999), pp. 436-445
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The diagnosis of ischaemic heart pain and intermittent claudication in field surveys.
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The Edinburgh Claudication Questionnaire: an improved version of the WHO/Rose Questionnaire for use in epidemiological surveys.
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Estimation of peripheral arteriosclerotic disease by ankle blood pressure measurements in a population study of 60 year old men and women.
J Chron Dis, 34 (1981), pp. 261-269
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Eur J Vasc Endovasc Surg., 20 (2000), pp. 336-341
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Prevalence of coexistence of coronary artery disease, peripheral arterial disease and aterothrombotic brain infarction in men and women < 62 years of age.
Am J Cardiol, 74 (1994), pp. 64-65
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Long-term survival in patients with coronary artery disease: importance of peripheral vascular disease.
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[15.]
T.R. Pedersen, J. Kjekshus, K. Pyorala, A.G. Olsson, T.J. Cook, T.A. Musliner, et al.
Effect of simvastatin on ischemic signs and symptoms in the Scandinavian simvastatin survival study (4S).
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[18.]
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[19.]
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Copyright © 2002. SEACV
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