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Pizarro Calderón, L. Pazó Sayos, M. Lema Tomé" "autores" => array:3 [ 0 => array:4 [ "nombre" => "A.G." "apellidos" => "Pizarro Calderón" "email" => array:1 [ 0 => "anagloriapizarro@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "L." "apellidos" => "Pazó Sayos" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Lema Tomé" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Anestesiología y Reanimación, Hospital Gregorio Marañón, Madrid, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Siempre alerta: errores de medicación" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1480 "Ancho" => 2507 "Tamanyo" => 525527 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Epidural pump, infusion system and identification labels: yellow for epidural use and blue for intravenous use.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Safety in the workplace is an essential part of quality care. Anaesthesiologists have been aware of the potential risks and adverse events associated with their daily activity. Specifically, adverse events due to medication errors are a major problem that have not only economical but also human repercussions. The ENEAS study<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a>, published in 2005, showed that 37.4% of adverse events that occur in relation to healthcare delivered in hospitals are due to medication errors.</p><p id="par0010" class="elsevierStylePara elsevierViewall">In 2010, the heads of the European anaesthesiology associations approved the Helsinki declaration on patient safety in anaesthesiology<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a>. The document discusses medication errors and the need to be aware of errors in the medication preparation phases, to double check, and the need to protocolise these processes. The Joint Commission<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> and the Institute for Safe Medication Practices<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> have made their own recommendations for reducing administration errors.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Errors in the preparation and administration of medication are very frequent (accounting for between 15% and 20% of incidents reported in our setting), and can be associated with morbidity. The platform most frequently used by anaesthesiologists to report these incidents is PITELO, available on the SENSAR website. We, as SENSAR analysts and members of our hospital’s Anaesthesiology and Resuscitation Safety Group, are responsible for receiving and analysing these notifications of critical incidents in order to prevent them from happening again. These are not isolated incidents or events exclusive to our hospital, but are repeated both nationally and internationally.</p><p id="par0020" class="elsevierStylePara elsevierViewall">Two events have prompted us to write this letter: the connection of an epidural PCA (patient-controlled analgesia) pump set to deliver 0.1% bupivacaine plus fentanyl to the peripheral line of 2 patients with epidural catheters. Both received intravenous boluses of this combination, but the attending nurses detected the error in time to prevent repercussions.</p><p id="par0025" class="elsevierStylePara elsevierViewall">After these incidents, which occurred in relatively quick succession, we analysed data from the SENSAR PITELO platform to determine the contributing factors and to propose corrective measures for each factor that would prevent these errors from recurring. We also performed a root cause analysis.</p><p id="par0030" class="elsevierStylePara elsevierViewall">In both cases, the PCA electronic prescription was correct and clearly specified the regimen and route of administration of the medication (<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>). The medication was correctly identified and prepared using the specific systems for epidural administration, and stickers had been placed on both the proximal and distal ends of the lines to indicate that they were intended for epidural use. As shown in the image, the pumps, the infusion system, and the identification labels are yellow for epidural use and blue for intravenous (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). Despite all the foregoing measures and existing safeguards, errors of this nature continue to occur, as shown by the incidents notified. This led us to wonder why these errors persist, and what additional measures can be put in place to prevent them.</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0035" class="elsevierStylePara elsevierViewall">We analysed the contributing factors using Reason’s Swiss cheese model, and came to the conclusion that the most important is the human factor, which is found in up to 50% of the critical incidents analysed. In this case, these human factors include:</p><p id="par0040" class="elsevierStylePara elsevierViewall">No safety culture: staff are unaware of the benefit of double checking, and do not correctly hand over patient information to their colleagues.</p><p id="par0045" class="elsevierStylePara elsevierViewall">Lack of attention, haste, work overload (particularly noticeable over this past year due to the pandemic), high staff turnover ratio.</p><p id="par0050" class="elsevierStylePara elsevierViewall">Absence of independent connection systems for intravenous and epidural lines that would prevent incorrect connections.</p><p id="par0055" class="elsevierStylePara elsevierViewall">This has prompted us to consider introducing new measures: new epidural systems with different connectors from those used in peripheral lines; medication error alerts that can be disseminated among staff; and periodic training sessions on the preparation and administration of drugs for all staff in all our units and wards, based, above all, on “the 10 correct procedures”<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a>:</p><p id="par0060" class="elsevierStylePara elsevierViewall">Patient: unequivocally confirm identity with name, surname, date of birth, etc.</p><p id="par0065" class="elsevierStylePara elsevierViewall">Drug: read the label and the container until you are sure that it is the drug that has been prescribed.</p><p id="par0070" class="elsevierStylePara elsevierViewall">Route of administration: check that both the route of administration and pharmaceutical form are correct.</p><p id="par0075" class="elsevierStylePara elsevierViewall">Take into account the prescribed administration schedules.</p><p id="par0080" class="elsevierStylePara elsevierViewall">Check the dose and the patient who will receive the drug.</p><p id="par0085" class="elsevierStylePara elsevierViewall">Tell the patient or their legal guardians how to use the PCA, what the drug is for and its possible side effects. This will encourage them to become involved in their own treatment.</p><p id="par0090" class="elsevierStylePara elsevierViewall">Correctly reconstitute the drug, indicate type and volume, expiration date, and where it should be stored.</p><p id="par0095" class="elsevierStylePara elsevierViewall">Method and rate of administration.</p><p id="par0100" class="elsevierStylePara elsevierViewall">Record the administration of the drug.</p><p id="par0105" class="elsevierStylePara elsevierViewall">Monitor the patient’s response after administration.</p><p id="par0110" class="elsevierStylePara elsevierViewall">Patient safety in anaesthesiology spans the entire perioperative period, from the moment the patient attends the pre-anaesthesia consultation until he or she is discharged from the hospital. We, as anaesthesiologists, must ensure that safety standards are met and that new measures are implemented to prevent further errors. Tools such as surgical checklists are a clear example of how small gestures can improve patient safety. Aside from our work in the operating room, we also need to be involved in analysing all the untoward incidents that occur on a day-to-day basis and propose measures to prevent their recurrence. In this regard, incident reporting systems are valuable tools that can improve patient safety and quality of care by helping professionals learn from mistakes in a systematic way.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Pizarro Calderón AG, Pazó Sayos L, Lema Tomé M. Siempre alerta: errores de medicación. Rev Esp Anestesiol Reanim. 2022. <span class="elsevierStyleInterRef" id="intr0005" href="https://doi.org/10.1016/j.redar.2021.05.004">https://doi.org/10.1016/j.redar.2021.05.004</span></p>" ] ] "multimedia" => array:2 [ 0 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1480 "Ancho" => 2507 "Tamanyo" => 525527 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Epidural pump, infusion system and identification labels: yellow for epidural use and blue for intravenous use.</p>" ] ] 1 => array:8 [ "identificador" => "tbl0005" "etiqueta" => "Table 1" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0010" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:1 [ "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black"> \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Sex \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Age \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">ASA \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Where detected \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Surgery \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Detected by \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Prescription labelling protocol \t\t\t\t\t\t\n \t\t\t\t\t\t</th><th class="td" title="\n \t\t\t\t\ttable-head\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Effect on the patient \t\t\t\t\t\t\n \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t ; 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entry_with_role_rowhead " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Patient 2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Female \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">39 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">II \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Recovery unit \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Obstetrics \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Nurse \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">Correct \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="\n \t\t\t\t\ttable-entry\n \t\t\t\t " align="left" valign="\n \t\t\t\t\ttop\n \t\t\t\t">None \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab2885773.png" ] ] ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Description of incidents.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Estudio nacional sobre los efectos adversos ligados a la hospitalización. ENEAS 2005" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "J.M. Aranaz" 1 => "C. Aibar" 2 => "J. Vitaller" 3 => "P. Ruiz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:3 [ "fecha" => "2006" "editorial" => "Ministerio de Sanidad y Consumo" "editorialLocalizacion" => "Madrid" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The Helsinki declaration on patient safety in anaesthesiology" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J. Mellin-Olsen" 1 => "S. Staender" 2 => "D.K. 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Journal Information
Vol. 69. Issue 3.
Pages 187-188 (March 2022)
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Vol. 69. Issue 3.
Pages 187-188 (March 2022)
Letter to the Director
Always on the alert: Medication errors
Siempre alerta: errores de medicación
A.G. Pizarro Calderón
, L. Pazó Sayos, M. Lema Tomé
Corresponding author
Servicio de Anestesiología y Reanimación, Hospital Gregorio Marañón, Madrid, Spain
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