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Vol. 27. Issue 4.
Pages 308-316 (October - December 2020)
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Vol. 27. Issue 4.
Pages 308-316 (October - December 2020)
Case report
DOI: 10.1016/j.rcreue.2020.01.007
Behçet's disease: a diagnostic challenge in rheumatology. Description of a case series and a review of the literature
Enfermedad de Behçet: un reto diagnóstico en reumatología. Descripción de una serie de casos y revisión de la literature
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D. Padilla-Ortiza, M. Chamorro-Melob, A.M. Santosa, J. Arias-Correala, V. Reyes-Martíneza, J.C. Ruedaa, J.M. Bello-Gualterob, E. Calvo-Páramoc, J. Londonoa,
Corresponding author
john.londono@unisabana.edu.co

Corresponding author.
a Grupo de Investigación Espondiloartropatías, Universidad de La Sabana – Hospital Militar Central, Bogotá, D.C., Colombia
b Servicio de Reumatología, Hospital Militar Central, Facultad de Medicina, Universidad Militar Nueva Granada, Bogotá, Colombia
c Departamento de Imágenes Diagnósticas, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, Colombia
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Table 1. Description of the demographic characteristics and clinical and laboratory findings.
Table 2. International criteria for the diagnosis of Behçet's disease (ICBD) 2014.
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Abstract

Behçet's disease is a clinical autoinflammatory disorder of unknown etiology, usually with systemic manifestations, and a pattern of exacerbation-remission, often associated with delayed diagnosis.

The diagnosis of this disease is complex. This article discusses four cases of patients with Behçet's disease, who during the clinical approach were considered to have other autoimmune diseases. A comprehensive review of the medical history, the development of oral and genital ulcers, in addition to the study of major histocompatibility complex typing (HLA), enabled the diagnosis of Behçet's disease.

Keywords:
Behçet's disease
Behçet's syndrome
Vasculitis
Systemic vasculitis
Blood vessels
Resumen

La enfermedad de Behçet (EB) es una entidad clínica autoinflamatoria, de etiología desconocida, generalmente con compromiso sistémico, con un patrón de exacerbación y remisión frecuente que se asocia a retraso en el diagnóstico.

El diagnóstico de esta enfermedad es complejo, por esta razón presentamos 4 casos de pacientes con EB, que durante el abordaje clínico fueron consideradas otras enfermedades de naturaleza autoinmune. La revisión integrada de la historia clínica, la aparición de úlceras orales y genitales, así como el estudio de tipificación del complejo mayor de histocompatibilidad (HLA) permitieron diagnosticar la EB.

Palabras clave:
Enfermedad de Behçet
Síndrome de Behçet
Vasculitis
Vasculitis sistémica
Vasos sanguíneos

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