Buscar en
Medicina Universitaria
Toda la web
Inicio Medicina Universitaria Scientific writing and editing, style " do" not matter, content barely does
Journal Information
Vol. 14. Issue 54.
Pages 42-46 (January 2012)
Download PDF
More article options
Vol. 14. Issue 54.
Pages 42-46 (January 2012)
Full text access
Scientific writing and editing, style " do" not matter, content barely does
Escritura y edición científica, el estilo "tá de más". el contenido apenas importa
Horacio Riveraa
a Doctorado en Genética Humana, Universidad de Guadalajara (CUCS) and Instituto Mexicano del Seguro Social (CIBO), Guadalajara, Jalisco, México.
Article information
Full Text
Download PDF

El crecimiento exponencial de investigadores y de revistas científicas (en su mayor parte en inglés), que florecieron después de la Segunda Guerra Mundial ha llevado inevitablemente a una multitud de argots especializados y una disminución de los estándares de la prosa científica. Para contrarrestar estas tendencias, la mayoría de los editores advierten a los potenciales autores acerca de la necesidad de corregir el estilo y la escritura, y ofrecen consejos a cerca de los recursos de edición disponibles. Sin embargo, nos encontramos comúnmente con manuscritos de mala calidad y que puede aparecer como artículos en revistas de buena reputación. Aquí, me referiré a cuatro manuscritos en idioma inglés (incluyendo uno en el cual soy co-autor) que fueron escritos por científicos hispanohablantes y que fueron publicados, a pesar de sus defectos, en tres revistas de tres editoriales científicas de gran reputación. Yo he mencionado estas fallas en tres Cartas al Editor, enviadas a las respectivas revistas con diferentes resultados: aceptación seguida de cancelación, retiro y rechazo. Tengo plena conciencia de los obstáculos que los escritores cuya lengua nativa no es el inglés tenemos para llegar a alcanzar un estilo adecuado en este idioma. Sin embargo, antes y más allá tienen del idioma que se use, las herramientas cruciales que necesita un científico (ya sea autor, revisor o editor) son un pensamiento lógico y un riguroso conocimiento científico. Espero que los subóptimos manuscritos antes mencionados, sean un aviso de que el proceso editorial, en revistas de tan respetadas casas editoriales como Elsevier, Springer-Verlag y Nature Publishing Group, no es infalible.

Palabras clave:
Redacción y edición científicas; estilo; revisión por pares; lógica; rigor académico

The exponential growth of researchers and scientific journals (mostly in English) that blossomed after World War II has inevitably led to a multitude of specialized jargons and to lower standards of scientific prose. To counteract these trends, most publishers warn potential authors about the need of correct style and writing and offer guidance on available editing resources; yet, poor quality manuscripts are common and may even appear as articles in reputable journals. I shall refer here to four English language papers (including one coauthored by myself) that were written by Spanish-speaking scientists and which were published, in spite of their defects, in three journals from three top scientific publishers. I have addressed these shortcomings in three Letters to the Editor submitted to the respective journals with different outcomes: acceptance followed by rescission, withdrawal, and rejection. I am fully aware of the hurdles that non-native English writers need to overcome in order to attain a suitable English style; however, before and beyond the language used, the crucial tools that a scientist needs (whether author, reviewer, or editor) are logical thought and rigorous scientific knowledge. I hope that the aforementioned suboptimal papers are a reminder that the editorial process in journals from such respected publishers as Elsevier, Springer-Verlag, and Nature Publishing Group is not infallible.

Scientific writing and edition; style; peer review; logical thought; scholarship
Full Text

The scientific writing in our journals exerts a corrupting influence on young scientists—on their writing, their reading, and their thinking. F.P. Woodford, 1967


The exponential growth of researchers and scientific journals (mostly in English) that blossomed after World War II has inevitably led to a multitude of specialized jargons and to lower standards of scientific prose.1-6 In his 1955 warning paper,7 Baker said "one hesitates to direct attention to this subject [clarity and directness in scientific writing] lest one be accused of setting oneself up as a stylist". Similar views have been held by other expert writers. Woodford8 concluded that "bad scientific writing... is often the outward and visible form of an inward confusion of thought" whereas Day2 emphasized the dictum that the "the best English is that which gives the sense in the fewest short words"; yet, poor quality articles are rather common and may even appear in reputable journals. To counteract these trends, most publishers warn potential authors of the need of proper writing and offer guidance to available resources.

I shall refer here to four papers (including one coauthored by myself) written in English by Spanish-speaking scientists and which were published, in spite of their poor scientific rigor and faulty language, in three journals from three top scientific publishers. I have addressed such shortcomings in Letters to the Editor (LE) submitted to the respective journals with the outcomes pointed out below (the original manuscripts and editorial correspondence are available upon request).

Paper A (remarks included in an accepted then rejected LE)

In our 2009 report of a 47,XXX/45,X/46,XX patient published in Fertility and Sterility 9 there is a noticeable contradiction. Such a logical flaw concerns the occurrence of müllerian malformations in 47,XXX women and is worded as follows: in the introduction we assert that "Renal and müllerian derivatives malformations have been described occasionally (3,4)" whereas in the discussion we say that "...müllerian malformations,,, are rather common in patients with Turner Syndrome with a structural abnormality of the X or Y (8), in 47,XXX females (9), and even in 45,X/47,XXX patients (10)".9 The former statement appears to be the correct one as it is consistent with the textbook assertion that prospective studies do not sustain the association of müllerian malformations with the 47,XXX condition.10 Moreover, the article by Sybert11 cited by us (reference four in our paper) to document the first statement is a review of 97 Turner syndrome patients with mosaicism for a 47,XXX clone but said nothing about müllerian anomalies. Two further out of context citations are included in our discussion assertion quoted above. The former reference eight has no bearing on Y-chromosome abnormalities,12 while the former reference nine only suggests a causal role of the XXX aneuploidy in the urogenital adysplasia sequence.13 Lastly, our report did not add any new knowledge to cytogenetic entities singled out since 1959.


On November 17, 2010, I submitted (with the appropriate "conflict of interest disclosure") a LE in Fertility and Sterility, which was immediately accepted. Yet, some days later, I received a rescission notice arguing that "...rather than become involved in any sort of intramural dispute between authors, it is in the best interest of the journal to rescind our acceptance of your letter for publication".

Papers B and C (remarks included in a submitted then withdrawn LE)

Gøtzsche et al14 have emphasized that "letters to the editor... may alert readers to limitations that have been overlooked by the authors, peer reviewers, and editors". Here, I make some remarks on two brief reports about systemic lupus erythematosus (SLE) in Mexican patients published in Rheumatology International:15,16

1. Since the population sample in the second paper16 seemingly is a subset of the subjects studied in the first report15 and given the complementary approaches, it would have been better to present all data in one article. Moreover, the authors' failure to cross-reference highlights an implicit salami-science strategy.

2. It is uncertain whether informed consent was obtained as both papers lack the required statement.

3. The one hundred fifty-three words discussion of the first report15 is unsubstantial and disregards the polymorphism's functional significance. Moreover, the study's aim of exploring the susceptibility to SLE or its clinical manifestations conferred by the allele V (176) conflicts with the fact that the "F158 allele is a risk factor for the development of lupus nephritis" (reference four cited therein) and with the final non sequitur sentence that the allele V (176) is not a protective factor.

4. In the second paper,16 the percentage of patients with SLE activity referred to as "15 (44.1%)" diverges from the expected 37.5% (15/40). It is not the reader who has to infer that 44.1% reflects the concealed proportion of 15/34 (six patients disappeared).

5. Some paragraphs of the first report15 such as the first two in material and methods and the third one in results have a faulty syntax and punctuation. There are also some concordance errors, missing words, and awkward constructs; e.g., the opening paragraph and the phrase "controls matched by a range of age and gender" in that report.

6. Regardless of whether the numerous authors (14 and nine) fulfill the criteria for responsible authorship or reflect dubious authorship practices,17 they did a suboptimal job.


On September 17, 2010, I submitted a LE to Rheumatology International but three weeks later (before an editorial decision was made), I decided to withdraw it due to fear of retaliation.

Paper D (remarks in a rejected LE)

Even if the author guidelines Even if the author guidelines of The Pharmacogenomics Journal strongly encourage non-native English writers to have their manuscripts corrected by either a proficient colleague or an English language editing service, this journal has published an article rich in language pitfalls.18 For instance, the verbiage and redundancy of the whole paper are well illustrated by the introductory assertion "methotrexate is the most commonly used disease modifying antirheumatic drug prescribed for AR". There are nonsensical sentences such as "heterozygosity for both polymorphisms have [sic] been related not only with reduced activity of the enzyme, but also with major concentration of total hcy in plasma and levels low of folate as homozygous patients for allele-mutated 677T" (second paragraph in introduction) or "some groups have reported association between MTHFR-C677T polymorphism and toxicity to MTX in Dutch and Japane- se population for one or the other allele" (note the ambiguity and lack of references in this sentence from the first paragraph in the discussion), and even logical flaws (does the 1298CC genotype protect against "efficacy"? first paragraph in discussion). In addition, there are at least six subject-verb or noun-pronoun disagreements.

Aside from these and other stylistic blemishes, the paper's design has the fatal flaw of failing to mention treatment duration; were the cases and controls treated for similar or different periods? In fact, most data gathered through the "structured questionnaire" were simply not included.


On December 16, 2010, I received a rejection letter regarding my LE submitted one month before to The Pharmacogenomics Journal.


Although my coauthorship in Paper A does not fulfill the International Committee of Medical Journal Editors' authorship criteria (given my meager revision of the paper's contents), I assume now my public responsibility for the shortcomings in our report. Yet, it is clear that our blatant mistakes, regardless of their scientific irrelevance, are no worse than the poor pre-publication peer review. Sadly, it seems that such an indulgent review is not an isolated fact in Fertility and Sterility as inferred from the sizeable proportion of missing references in the report of a 45,X male.19 Further, I assert that the disagreement with other co-authors on how to amend our own mistakes is overwhelmed by the serious flaws in our report. In any case, the point is not if my colleagues are upset but the moral and academic responsibility common to all research's actors (authors, referees, editors, administrators, readers, etc) to keep the record straight. Otherwise, we have to concur with the old saying highlighted by Day:2 "A scientific paper is not designed to be read. It is designed to be published".

I recognize my susceptibility to the "Mohammed Ali effect"20 and that questionable research practices are rather common and play a "useful and irreplaceable role".21 Yet, they must be prevented through training in the responsible conduct of research22-24 and by the example set by (good and bad) mentors.25 Based on comparable personal experiences,26 I anticipate that the colleagues here alluded to will attempt to dismiss these criticisms - even with ad hominem arguments - instead of offering rational explanations. The blemishes here remarked also illustrate the questionable communication practices highlighted by Roland27 which are consistent with her conclusion that the "majority of researchers felt rather comfortable with the usual scientific style".

According to the Committee on Publication Ethics' code of conduct for editors28 these gatekeepers should, among other duties, "ensure the quality of published material, retract fraudulent or erroneous articles, publish cogent criticisms from readers, and stand for decisions to publish papers unless serious problems are found". So, the first case (Paper A) here described further emphasizes the disadvantageous position of authors vis à vis editors and reviewers.26,29,30

Although the authors of all four papers here commented on are primarily responsible for the quality of the published material, the co-responsibility of the respective reviewers cannot be overlooked. Once thought as the guarantor of academic quality, pre-publication peer review appears to be declining and its proclaimed rigor vanishing.30-32 Even if this trend can be related to the exponential growth of scientists and scientific publications, all of us involved in the publishing game must attempt to improve or at least preserve the quality and rigor inherent to science itself.

Obviously, I'm fully aware of the hurdles that non-native English writers have to overcome in order to attain a suitable English style.5 Yet, before and beyond the language used, the crucial tools for a scientist (whether author, reviewer, or editor) are logical thought and rigorous knowledge. I hope that the aforementioned suboptimal papers remind us that the editorial process in journals from such respected publishers as Elsevier, Springer-Verlag, and Nature Publishing Group is not infallible.

Conflict of interest disclosure

I declare to have academic links with several authors of the reports here commented on. Actually, I have been their instructor on matters such as scientific writing and publication ethics.

Corresponding author: Horacio Rivera,

División de Genética, CIBO-IMSS, Sierra Mojada 800, C.P. 44340. Guadalajara, Jalisco, México.

E-mail: hrivera@cencar.udg.mx.

Received: October 2011.

Accepted: November 2011

Aaronson S..
Style in scientific writing..
, 20 (Curr Cont 1977), pp. 6-15
Day RA..
How to Write and Publish a Scientific Paper. Philadelphia..
ISI Press. , 4-5 (1979),
Woodford FP..
Scientific Writing for Graduate Students. Bethesda..
Council of Biology Editors, Inc. , 34-58 (1986),
Knight J..
Clear as mud..
, 422 (Nature 2003), pp. 376-378
Day RA, Gastel B..
How to Write and Publish a Scientific Paper. 6th Edition. Westport..
CT: Greenwood Press. , 215-219 (2006),
Ludbrook J..
Writing intelligible English prose for biomedical journals..
, 34 (Clin Exp Pharmacol Physiol 2007), pp. 508-514
Baker JR..
English style in scientific papers..
, 176 (Nature 1955), pp. 851-852
Woodford FP..
Sounder thinking through clearer writing..
, 156 (Science 1967), pp. 743-745
Brambila-Tapia AJL, Rivera H, García-Castillo H, et al..
47,XXX/45,X/46,XX mosaicism in a patient with Turner phenotype and spontaneous puberal development..
, 92:1747.e5-7 (Fertil Steril 2009),
Allanson JE, Graham GE..
Sex chromosome abnormalities. In: Rimoin DL, Connor JM, Pyeritz RE, Korf BR (editors), Emery and Rimoin''s Principles and Practice of Medical Genetics. 4th Edition, London. Churchill Livingstone..
2002. , (1195-1196),
Sybert VP..
Phenotypic effects of mosaicism for a 47,XXX cell line in Turner syndrome..
, 39 (J Med Genet 2002), pp. 217-221
Güven A, Kara N, Saðlam Y, et al..
The Mayer-Rokitansky-Kuster-Hauser and gonadal dysgenesis anomaly in a girl with 45,X/46,X,del(X)(p11..
21). , 146A (Am J Med Genet 2008), pp. 128-131
Hogge WA, Vick DJ, Schnatterly PA, MacMillan RH..
Bilateral renal agenesis and Mullerian anomalies in a 47,XXX fetus..
, 33 (Am J Med Genet 1989), pp. 242-243
Gøtzsche PC, Delamothe T, Godlee F, et al..
Adequacy of authors'' replies to criticism raised in electronic letters to the editor: cohort study..
, 341 (BMJ 2010), pp. c3926
Brambila-Tapia AJL, Gámez-Nava JI, González-López L, et al..
FCGR3A V(176) polymorphism for systemic lupus erythematosus susceptibility in Mexican patients..
, 31 (Rheumatol Int 2010), pp. 1065-1068
Brambila- Tapia AJL, Gámez-Nava JI, Salazar-Páramo M, et al..
Increased CD28 serum levels are not associated with specific clinical activity in systemic lupus erythematosus..
, 31 (Rheumatol Int 2010), pp. 1321-1324
Tice PP..
Contributorship: promoting greater authorship integrity..
, 20 (AMWAJ 2005), pp. 7-9
Mena JP, Salazar-Páramo M, González-López L, et al..
Polymorphisms C677T and A1298C in the MTHFR gene in Mexican patients with rheumatoid artritis treated with methotrexate: implication with elevation of transaminases..
, 11 (Pharmacogenomics J 2010), pp. 287-291
Rivera H..
45,X infertile males: not so rare..
, 92 (Fertil Steril 2009), pp. e49
Fanelli D..
How many scientists fabricate or falsify research? A systematic review and meta-analysis of survey data..
, 4 (PLoS ONE 2009), pp. e5738
De Vries R, Anderson MS, Martinson BC..
Normal misbehavior: scientists talk about the ethics of research..
, 1 (J Empir Res Hum Res Ethics 2006), pp. 43-50
Roland MC..
Who is responsible?..
, 8 (EMBO Rep 2007), pp. 706-711
Nylenna M, Simonsen S..
Scientific misconduct: a new approach to prevention..
, 367 (Lancet 2006), pp. 1882-1884
Titus SL, Wells JA, Rhoades LJ..
Repairing research integrity..
, 453 (Nature 2008), pp. 980-981
Leading by example. , 445 (Nature 2007), pp. 229
Rivera H..
Editors'' malpractice: forward submitted letters (to the concerned authors), then reject them..
, 16 (Account Res 2009), pp. 331-333
Roland MC..
Quality and integrity in scientific writing: prerequisites for quality in science communication..
, 08 (Jcom 2009), pp. A04
Godlee F..
Dealing with editorial misconduct..
New code of conduct for editors is a first step in self regulation. , 329 (BMJ 2004), pp. 1301-1302
Shamoo AE..
Editors, peer reviews, and ethics..
Newton DP..
Quality and peer review of research: an adjudicating role for editors..
, 17 (Account Res 2010), pp. 130-145
Smith R..
Peer review: a flawed process at the heart of science and journals..
, 99 (J R Soc Med 2006), pp. 178-182
Smith R..
Classical peer review: an empty gun..
, 12 (Breast Cancer Res 2010), pp. S13
Article options