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Inicio Medicina Clínica (English Edition) Ultrasonographic features of arthritis in patients with primary Sjögren's s...
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Vol. 157. Issue 11.
Pages 507-512 (December 2021)
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Vol. 157. Issue 11.
Pages 507-512 (December 2021)
Original article
Ultrasonographic features of arthritis in patients with primary Sjögren's syndrome and its clinical significance
Características ecográficas de la artritis en pacientes con síndrome de Sjögren primario y su significación clínica
Shasha Wang, Qin Shao
Corresponding author

Corresponding author.
Department of Rheumatology, Chongqing Traditional Chinese Medicine Hospital, Chongqing 400021, China
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Figures (2)
Tables (3)
Table 1. Joint distribution with US lesions (number of cases).
Table 2. Semi-quantitative score of US lesions (number of cases).
Table 3. Comparison of clinical manifestations between the two groups of patients.
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To observe the ultrasonographic features of arthritis in patients with primary Sjögren's syndrome (pSS) and to analyze its correlation with clinical manifestations and disease activity.


Ultrasound (US) examinations were performed in a total of 1200 joints of 40 patients with pSS. A semi-quantitative grading method (0–3) for scoring synovial hyperplasia, PD synovitis, bone erosion, tenosynovitis was used. The clinical and laboratory data were collected, disease activity was assessed. The correlation between US lesions and disease activity assessment and clinical manifestations was analyzed.


US findings of musculoskeletal in patients with pSS mainly involved the small joints of the hands and wrists and the lesions were mild. The semi-quantitative score of musculoskeletal US was positively correlated with ESSPRI. The occurrence of musculoskeletal US lesions is associated with immunological abnormalities and inflammatory markers, and patients with high IgG, RF, and inflammatory markers are prone to abnormal US findings.


The incidence of arthritis in patients with pSS is high, and musculoskeletal US has its characteristics. The musculoskeletal US semi-quantitative method can effectively evaluate arthritis in patients with pSS, and the US score of arthritis has a certain correlation with the overall disease activity. US can provide a reference for the diagnosis of arthritis and disease activity assessment in patients with pSS.

Sjögren's syndrome
Disease activity

Observar las características ecográficas de la artritis en pacientes con síndrome de Sjögren primario (SSp), y analizar su correlación con las manifestaciones clínicas y la actividad de la enfermedad.


Se realizaron exámenes ecográficos (EE) en un total de 1.200 articulaciones de 40 pacientes con SSp. Se utilizó un método de valoración semicuantitativa (de 0 a 3) para clasificar hiperplasia sinovial, sinovitis PD, erosión ósea y tenosinovitis. Se recopilaron los datos clínicos y de laboratorio y la actividad de la enfermedad. Se analizó la correlación entre lesiones detectadas por EE y evaluación de la enfermedad y manifestaciones clínicas.


Los hallazgos musculoesqueléticos detectados por EE en pacientes con SSp comprometían principalmente las articulaciones pequeñas de las manos y muñecas, siendo las lesiones de carácter leve. La valoración semicuantitativa de los EE musculoesqueléticos se correlacionó positivamente con ESSPRI. La incidencia de lesiones musculoesqueléticas detectadas por EE está asociada a alteraciones inmunológicas y marcadores inflamatorios, siendo más propensos los pacientes con altos valores de IgG, RF y marcadores inflamatorios a los hallazgos EE anormales.


La incidencia de artritis en pacientes con SSp es elevada, y los EE musculoesqueléticos tienen sus características. El método semicuantitativo de los EE musculoesqueléticos puede evaluar de manera efectiva la artritis en pacientes con SSp, teniendo la valoración de la artritis de los EE una cierta correlación con la actividad de la enfermedad global. EE puede aportar referencia al diagnóstico de la artritis y la evaluación de la actividad de la enfermedad en pacientes con SSp.

Palabras clave:
Síndrome de Sjögren
Actividad de la enfermedad


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