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Inicio Medicina Clínica (English Edition) Surgical approach of non-small cell lung cancer with extrapulmonary metastasis
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Vol. 153. Issue 3.
Pages 115-121 (August 2019)
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Vol. 153. Issue 3.
Pages 115-121 (August 2019)
Surgical approach of non-small cell lung cancer with extrapulmonary metastasis
Abordaje quirúrgico del carcinoma broncogénico de células no pequeñas con metástasis extrapulmonar
Gemma María Muñoz Molinaa,
Corresponding author

Corresponding author.
, Ana Patricia Ovejero Díaza, Luis Gorospe Sarasúab
a Cirugía Torácica, Hospital Ramón y Cajal, Madrid, Spain
b Radiodiagnóstico, Hospital Ramón y Cajal, Madrid, Spain
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Tables (2)
Table 1. Recommendations for the treatment of brain metastases.
Table 2. Recommendations for the treatment of adrenal metastases.
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Bronchogenic carcinoma is the leading cause of death due to cancer worldwide. Nearly 75% of patients have a disseminated carcinoma at diagnosis. Up to 50% of patients with a localized disease will develop metastasis. Nevertheless, the current scientific evidence has demonstrated that when the metastatic disease is limited, particularly in specific locations such as the brain and the adrenal glands, a multidisciplinary approach with radical intent could achieve a longer survival.

This review analyses the clinical evidence available in the literature that supports the treatment of both the primary and the metastatic disease, as well as the preoperative study and the most widely accepted indications.

Non small-cell lung cancer
Cerebral metastases
Adrenal metastases

El carcinoma broncogénico es la causa más frecuente de muerte por cáncer en el mundo. Cerca del 75% de los pacientes presentan enfermedad diseminada en el momento del diagnóstico. Hasta un 50% de los pacientes con enfermedad localizada al inicio desarrollarán metástasis. Sin embargo, la evidencia científica actual ha demostrado que, cuando la enfermedad metastásica es limitada y sobre todo en determinadas localizaciones como la cerebral y la suprarrenal, su abordaje multidisciplinar con intención radical puede prolongar la supervivencia.

El presente artículo revisa la evidencia clínica bibliográfica existente que apoya el tratamiento, no solo de la enfermedad primaria sino de la metastásica, además del estudio preoperatorio y las indicaciones más aceptadas.

Palabras clave:
Carcinoma broncogénico de células no pequeñas
Metástasis cerebral
Metástasis suprarrenal


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