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Vol. 154. Issue 2.
Pages 52-54 (January 2020)
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Vol. 154. Issue 2.
Pages 52-54 (January 2020)
Brief report
Role of antiplatelet therapy in the development of intracranial bleeding after mild traumatic brain injury
Papel de la terapia antiagregante en el desarrollo de hemorragia intracraneal tras traumatismo craneal leve
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Miguel Genebat Gonzáleza,
Corresponding author
mgenebat@yahoo.es

Corresponding author.
, Reginald Dusseck Brutusb, Ángel García-Olloquia, Horacio García-Delgado Rosadob, Rafael Bellido Albab, Ignacio Pérez Torresa
a Servicio de Urgencias, Hospital Universitario Virgen del Rocío, Sevilla, Spain
b Unidad de Cuidados Intensivos, Hospital Universitario Virgen del Rocío, Sevilla, Spain
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Tables (3)
Table 1. General baseline characteristics of the sample (n=566).
Table 2. Comparison between patients based on the result of computed tomography (CT) scan.
Table 3. Factors associated with haemorrhagic intracranial injury after mild head trauma.
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Abstract
Introduction and objective

The use of antiplatelet agents is increasing, mainly in elderly patients in whom cranial trauma is a frequent reason for consultation to the emergency department. In this context, discordances have been described regarding the increased risk of post-traumatic injury that involves taking antiplatelet drugs. Therefore, the objective of this present study was to analyse factors associated with intracranial bleeding after mild brain trauma.

Patients and methods

A retrospective study was designed that included all patients who had consulted the emergency department during 2016 because of mild brain trauma (Glasgow coma scale 14–15) and excluded patients under anticoagulant therapy. A logistic regression analysis was performed to analyse the variables associated with intracranial bleeding.

Results

566 patients were included in the study. 18% of them were taking antiplatelet drugs. Tomography showed haemorrhagic intracranial damage in 16.1%. Factors associated with intracranial bleeding were: advanced age, Glasgow coma scale <15, high-energy trauma and antiplatelet therapy.

Discussion

Antiplatelet therapy emerges as a risk factor for intracranial bleeding after mild head trauma, in addition to other known factors.

Keywords:
Brain injury
Intracranial bleeding
Antiplatelet therapy
Resumen
Introducción y objetivo

El uso de antiagregantes plaquetarios está aumentando, fundamentalmente en pacientes de edad avanzada en los que el traumatismo craneal es un motivo habitual de consulta en urgencias. En este contexto existe discordancia sobre el riesgo aumentado de lesión postraumática que supone la toma de antiagregantes. Por tanto, el objetivo de este estudio fue analizar los factores asociados con la presencia de sangrado intracraneal tras traumatismo craneoencefálico leve.

Pacientes y métodos

Se diseñó un estudio retrospectivo, incluyendo todos aquellos pacientes atendidos en 2016 por traumatismo craneoencefálico leve (escala de coma de Glasgow 14-15), excluyendo los pacientes en tratamiento anticoagulante. Se realizó un análisis de regresión logística para analizar las variables asociadas con sangrado intracraneal.

Resultados

Quinientos sesenta y seis pacientes fueron incluidos. El 18% de los pacientes tomaba antiagregantes. La tomografía mostró lesión intracraneal hemorrágica en el 16,1%. Los factores asociados con sangrado intracraneal fueron: edad avanzada, escala de coma Glasgow<15, traumatismo de alta energía y toma de antiagregantes.

Discusión

La terapia antiagregante emerge como factor de riesgo de sangrado intracraneal tras traumatismo craneoencefálico leve, además de otros factores ya conocidos.

Palabras clave:
Traumatismo craneal
Sangrado intracraneal
Terapia antiagregante

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