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Inicio Medicina Clínica (English Edition) Rhabdomyolysis: A syndrome to be considered
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Vol. 158. Issue 6.
Pages 277-283 (March 2022)
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Vol. 158. Issue 6.
Pages 277-283 (March 2022)
Review
Rhabdomyolysis: A syndrome to be considered
Rabdomiólisis: un síndrome a tener en cuenta
Visits
36
Ramón Baeza-Trinidad
Servicio de Medicina Interna, Hospital San Pedro, Logroño, Spain
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Table 1. Drugs related to rhabdomyolysis.
Table 2. Variables of the acute renal failure score in rhabdomyolysis20.
Table 3. Treatment of rhabdomyolysis.
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Abstract

Rhabdomyolysis is characterized by the release of intracellular elements after the destruction of skeletal muscle. Is characterized by the presence of muscle pain, weakness, and dark urine, associated with elevated creatine kinase (CK). The causes related to this syndrome are varied, being traumatic etiology, immobilization, sepsis, drugs and alcohol the most frequent. CK values are used for diagnosis and prognosis, being renal dysfunction the most serious complication. Treatment is based on early and intensive fluid therapy to avoid kidney complications.

Keywords:
Rhabdomyolysis
Creatine kinase
Myoglobin
Acute kidney injury
Resumen

La rabdomiólisis es una entidad clínica caracterizada por la liberación de elementos intracelulares tras la destrucción del músculo esquelético. La tríada clásica se caracteriza por la presencia de dolor muscular, debilidad y orina oscura, asociada a elevación de la creatincinasa (CK). Las causas relacionadas con este síndrome son variadas, siendo la etiología traumática, inmovilización, sepsis, drogas, fármacos y alcohol, las más frecuentes. Los valores de CK son utilizados como diagnóstico y pronóstico, siendo la disfunción renal la complicación más grave. El tratamiento se basa en la fluidoterapia intensiva y precoz para evitar complicaciones renales.

Palabras clave:
Rabdomiólisis
Creatincinasa
Mioglobina
Fracaso renal agudo

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