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Inicio Medicina Clínica (English Edition) Primary cutaneous B-cell lymphomas: Study of 22 cases
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Vol. 147. Issue 5.
Pages 207-210 (September 2016)
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Vol. 147. Issue 5.
Pages 207-210 (September 2016)
Clinical report
DOI: 10.1016/j.medcle.2016.06.053
Primary cutaneous B-cell lymphomas: Study of 22 cases
Linfomas B cutáneos primarios: estudio de 22 casos
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Pablo Martín Carrascoa,
Corresponding author
Pablo_ronda@hotmail.com

Corresponding author.
, Mercedes Morillo Andújara, Carmen Pérez Ruiza, Teresa de Zulueta Doradob, Rocío Cabrera Pérezb, Julián Conejo-Mira
a Unidad de Gestión Clínica de Dermatología, Hospital Universitario Virgen del Rocío, Sevilla, Spain
b Unidad de Gestión Clínica de Anatomía Patológica, Hospital Universitario Virgen del Rocío, Sevilla, Spain
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Tables (2)
Table 1. Age, subtype, staging at diagnosis, initial treatment, relapse and treatment and follow-up of the 22 primary cutaneous B-cell lymphomas.
Table 2. Markers and mutations of the 22 primary cutaneous B-cell lymphomas.
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Abstract
Introduction and objectives

Primary cutaneous B-cell lymphoma (CBCL) is a very low prevalence neoplasm and constitutes 25% of all primary cutaneous lymphomas. Our objective was to discover the epidemiological, clinic and histologic characteristics of CBCL in our area.

Methods

Retrospective descriptive study with patients with histologic diagnosis of CBCL followed up in our department between 2004 and 2015.

Results

Twenty-two patients with CBCL were included; 65% were men and 35% were women. Follicle centre lymphoma was the most common subtype (41%). Only 3 cases presented with node involvement and one with bone marrow invasion. Five recurrences were detected and one patient died because of the CBCL.

Discussion and conclusions

This is one of the first CBCL series in theSpanish population. The incidence, sex, age, subtype distribution, clinical features and immunohistochemical patterns are very similar to those of the other series.

Keywords:
B-cell cutaneous lymphoma
Follicle centre lymphoma
Primary cutaneous marginal zone lymphoma
Primary cutaneous diffuse large B-cell lymphoma leg-type
Resumen
Introducción y objetivos

El linfoma B cutáneo primario (LBCP) es una neoplasia de muy baja prevalencia y supone un 25% de todos los linfomas cutáneos. Nuestro objetivo era conocer las características epidemiológicas, clínicas e histológicas de los LBCP de nuestra área sanitaria.

Métodos

Estudio descriptivo retrospectivo con datos de los pacientes con diagnóstico anatomopatológico de LBCP seguidos entre los años 2004 y 2015 en el Hospital Universitario Virgen del Rocío.

Resultados

Se incluyeron 22 casos de pacientes con LBCP. El 65% eran varones frente a un 35% de mujeres. El linfoma centrofolicular supuso el subtipo más frecuente (41%). Tres casos desarrollaron afectación ganglionar y uno, invasión de la médula ósea. Durante el seguimiento se observaron 5 recidivas y un paciente falleció a causa de su LBCP.

Discusión y conclusiones

Aportamos una de las primeras series de pacientes con LBCP descritas en población española. La incidencia detectada en nuestra área es similar a las de otras poblaciones descritas en la literatura. Respecto al sexo, la edad, la distribución por subtipos y la presentación clínica e inmunohistoquímica, también se obtuvieron datos similares a los de otras series.

Palabras clave:
Linfoma B cutáneo
Linfoma cutáneo centrofolicular
Linfoma cutáneo zona marginal
Linfoma cutáneo tipo pierna

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