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Vol. 161. Issue 2.
Pages 49-53 (July 2023)
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Vol. 161. Issue 2.
Pages 49-53 (July 2023)
Original article
Prevalence and pattern of alcohol consumption in patients with hepatocellular carcinoma
Prevalencia y patrón de consumo de alcohol en pacientes con carcinoma hepatocelular
Daniel Muiño-Domíngueza, Alejandro Mínguez-Sabaterb, Eduardo Junquera-Alonsoc, Ana María Piedra-Cerezala, Manuel Rodrígueza,d,e, María Varelaa,d,e,f,
Corresponding author
a Unidad de Hepatología, Servicio de Digestivo, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain
b Unidad de Hepatología, Servicio de Digestivo, Hospital Universitario y Politécnico La Fe, Valencia, Spain
c Sección de Digestivo, Servicio de Medicina Interna, Hospital Universitario San Agustín, Avilés, Asturias, Spain
d Departamento de Medicina, Universidad de Oviedo, Oviedo, Asturias, Spain
e Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Asturias, Spain
f Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Oviedo, Asturias, Spain
Article information
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Tables (2)
Table 1. Patient characteristics according to the presence of alcohol consumption.
Table 2. Drinking patterns.
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Abstract
Aim

Prospective cross-sectional study conducted to determine the prevalence and pattern of alcohol consumption (AC) in patients with hepatocellular carcinoma (HCC) and to assess the utility of the AUDIT in HCC patients.

Methods

One hundred and two consecutive patients form our HCC monographic outpatient clinic visited between February and March 2022 were included. Patients with hepatic encephalopathy at the time of the interview, on the waiting list for liver transplantation and those undergoing post-transplant follow-up were excluded.

Results

The prevalence of AC in patients diagnosed with HCC is 35%, although less than 10% consume more than 100 g per week. AC was more frequent in males, in an urban environment, with a diagnosis of HCC more than a year ago, and in patients in early/very early stages of BCLC. AUDIT score greater than or equal to 3 (AUROC 0.849) predicts any AC with a sensitivity of 75% (95% CI: 59.47–90.53%) and a specificity of 84% (95% CI: 74.70–94.05%).

Conclusions

Despite the diagnosis of HCC, more than a third of the patients consume alcohol. An AUDIT score equal to or greater than 3 discriminates any AC with a sensitivity of 75% and a specificity of 84% in this population.

Keywords:
Hepatocellular carcinoma
BCLC
Standard drink unit
AUDIT
Resumen
Objetivo

Estudio transversal prospectivo realizado para conocer la prevalencia y patrón de consumo de alcohol (CA) de los pacientes con carcinoma hepatocelular (CHC) y evaluar la utilidad del AUDIT, en pacientes con CHC.

Métodos

Se incluyeron 102 pacientes consecutivos atendidos en consulta entre febrero y marzo de 2022, se excluyeron aquellos con encefalopatía hepática en el momento de la entrevista, pacientes en lista de espera para trasplante por esta indicación y aquellos en seguimiento post-trasplante.

Resultados

La prevalencia del CA en pacientes con diagnóstico de CHC es del 35%, si bien menos del 10% consume más de 100 gramos de etanol a la semana. El CA fue más frecuente en varones, ambiente urbano, con diagnóstico de CHC hace más de un año y en pacientes en estadio inicial/muy inicial del BCLC. La puntuación AUDIT mayor o igual a 3 (AUROC 0,849) predice cualquier CA con una sensibilidad del 75% (IC 95%: 59,47–90,53%) y con una especificidad del 84% (IC 95%: 74,70–94,05%).

Conclusiones

A pesar del diagnóstico de CHC más de un tercio de los pacientes consume alcohol. La puntuación AUDIT igual o más que 3 discrimina cualquier CA con una sensibilidad del 75% y una especificidad del 84% en esta población.

Palabras clave:
Carcinoma hepatocelular
BCLC
Unidad de bebida estándar
AUDIT

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