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Inicio Medicina Clínica (English Edition) Positive urine pneumococcal antigen test and vaccination
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Vol. 146. Issue 8.
Pages 346-347 (April 2016)
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Vol. 146. Issue 8.
Pages 346-347 (April 2016)
Brief report
Positive urine pneumococcal antigen test and vaccination
Antigenuria positiva a neumococo y vacunación
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Alejandro Salinas-Botrána,
Corresponding author
asalinasbotran@yahoo.es

Corresponding author.
, Patricia Martín-Ricoa, Antonio Valdiviab, Ángel Pellicerc, Óscar Esparciad
a Servicio de Medicina Interna, Hospital de Denia, Denia, Alicante, Spain
b Servicio de Medicina Preventiva, Hospital de Denia, Denia, Alicante, Spain
c Servicio de Medicina Interna, Consorcio Hospital General Universitario de Valencia, Valencia, Spain
d Servicio de Microbiología, Hospital de Denia, Denia, Alicante, Spain
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Med Clin. 2016;146:348-910.1016/j.medcle.2016.06.012
Rafael Zalacain
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Table 1. Radiographic pneumonia and vaccination (Pneumo-23, Pneumo-13).
Abstract
Introduction and objective

Although urine pneumococcal antigen is an useful test, it has false positives such as pneumococcal vaccination.

Material and methods

Positive urine pneumococcal antigen in Hospital de Denia (January–February/2015). We studied epidemiological, radiological and microbiological variables as well as previous pneumococcal vaccination (Pneumo-23 and/or Pneumo-13).

Results

Urine pneumococcal antigen test was positive in 12.4% of 385 cases. Only 33.3% of positive cases had pneumonia in chest X-ray, and 35.4% of patients had previous pneumococcal vaccination. In most cases (87.5%), an antibiotic was prescribed.

Conclusions

Pneumococcal vaccination can produce a false positive result in the urine pneumococcal antigen test in clinical practice, leading to an unnecessary prescription of antibiotics.

Keywords:
Pneumococcus
Vaccination
False positive
Resumen
Introducción y objetivo

La detección del antígeno neumocócico en orina es una prueba útil pero puede presentar falsos positivos, entre ellos, la vacunación neumocócica.

Material y métodos

Detección de las antigenurias positivas a neumococo en el Hospital de Denia (enero-febrero/2015). Se determinaron variables epidemiológicas, radiológicas, microbiológicas y antecedente de vacunación neumocócica (neumo-23 y/o neumo-13).

Resultados

La antigenuria a neumococo mostró un resultado positivo en el 12,4% de 385 determinaciones. Solo en el 33,3% de los casos con antigenuria positiva se documentó infiltrado radiológico en la radiografía de tórax. En el 35,4% de los pacientes existía antecedente de vacunación neumocócica previa. En la mayor parte de los casos (87,5%) un antígeno neumocócico positivo supuso la prescripción de un tratamiento antibiótico.

Conclusiones

La vacunación neumocócica puede generar falsos positivos a la antigenuria por neumococo en la práctica clínica, con la consiguiente prescripción innecesaria de antibióticos en gran número de casos.

Palabras clave:
Neumococo
Vacunación
Falso positivo

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