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Vol. 145. Issue 9.
Pages 404-408 (November 2015)
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Vol. 145. Issue 9.
Pages 404-408 (November 2015)
Review
DOI: 10.1016/j.medcle.2016.03.006
Oral precancer and cancer
Precáncer y cáncer bucal
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José López-Lópeza, Carlos Omaña-Cepedab, Enric Jané-Salasa,
Corresponding author
enjasa19734@gmail.com

Corresponding author.
a Departamento de Odontoestomatología, Facultad de Odontología, Universidad de Barcelona, l’Hospitalet de Llobregat, Barcelona, Spain
b Máster de Odontología en Pacientes Oncológicos e Inmunocomprometidos, Facultad de Odontología, Universidad de Barcelona, l’Hospitalet de Llobregat, Barcelona, Spain
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Tables (4)
Table 1. Potentially malignant lesions in the oral cavity.
Table 2. Clinical classification of leukoplakia based on the criteria provided by the Conference of Uppsala.
Table 3. Criteria for malignancy of oral lichen planus.
Table 4. Attitude of dentist against oral cancer.
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Abstract

We reviewed the concept of oral precancerous lesions, oral cancer, and the possibility of early diagnosis. With the keywords: premalignant oral lesions prevention, a search was performed over the past 10 years. Also clinical trials are searched from January 2011 until today with the keywords: oral cancer prevention AND dentistry. It is emphasized that there can be no significant changes related to the concept of precancerous lesions and cancer, and those relating to the early diagnosis. Despite the numerous described methods of screening, biopsy remains the most useful test, and therefore it is essential, mainly if we consider the new possibilities of molecular studies.

Keywords:
Cancer
Precancer
Pre-malignant lesions
Malignant lesions
Potentially malignant disorders
Oral lichen planus
Leukoplakia
Resumen

Se revisa el concepto de lesiones precancerosas orales, de cáncer oral y su diagnóstico precoz. Con las palabras clave: premalignant oral lesions prevention se realiza una búsqueda de los 10 últimos años. También se buscan los ensayos clínicos desde enero de 2011 hasta la actualidad con las palabras clave: oral cancer prevention AND dentistry. Se destaca que no hay cambios significativos relacionados con el concepto de lesión precancerosa y cáncer, y que en cuanto al diagnóstico precoz, si bien se describen numerosos métodos de cribado, la biopsia sigue siendo la prueba más útil y, por tanto, imprescindible, más aún si consideramos las nuevas posibilidades de estudios moleculares.

Palabras clave:
Cáncer
Precáncer
Lesiones premalignas
Lesiones malignas
Lesiones potencialmente malignas
Liquen plano oral
Leucoplasia

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