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Vol. 157. Issue 4.
Pages 178-184 (August 2021)
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Vol. 157. Issue 4.
Pages 178-184 (August 2021)
Review
DOI: 10.1016/j.medcle.2021.02.005
Kidney and hypertension in older adults
Riñón e hipertensión en el anciano
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Hanane Bouaricha, Alina Chávez Guilléna, Diego Rodríguez Puyola,b,
Corresponding author
drodriguez.hupa@gmail.com

Corresponding author.
a Sección de Nefrología, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, Spain
b Departamento de Medicina y Especialidades Médicas, Universidad de Alcalá, IRYCIS, Alcalá de Henares, Madrid, Spain
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Tables (3)
Table 1. Renal structural changes.
Table 2. Renal functional changes.
Table 3. Blood pressure therapeutic targets in people over 65 years of age according to the Consensus Guidelines for HTN.
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Abstract

Individuals over 65 years are the fastest expanding population throughout the world, due to the increase in human life expectancy. This growing geriatric population, with increasingly associated chronic diseases, has relevant medical, social, and economic impact. Aging is characterized by progressive structural and functional changes in the kidney and in the cardiovascular system, leading to decline in renal function and hypertension. The purpose of this review is to describe the aging-related renal changes and blood pressure regulation during the aging process and their impact with regards to morbidity and mortality in these patients. And to summarize the most appropriate therapeutic approaches in these situations based on the particularities of this population group.

Keywords:
Aging
Kidney
Hypertension
Cardiovascular risk
CKD
Resumen

Con el incremento de la esperanza de vida de la población, las personas mayores de 65 años son un grupo cada vez más prevalente, con el consiguiente aumento de patologías crónicas asociadas, desencadenando un escenario de gran impacto sociosanitario. Durante el proceso de envejecimiento, se producen cambios tanto estructurales como funcionales en el riñón y en el sistema cardiovascular, que condicionan la aparición de alteraciones de la función renal e HTA, problemas de salud de primer orden en la actualidad. El objetivo de esta revisión es describir los cambios en la función renal y en la regulación de la presión arterial con el envejecimiento, su impacto clínico, en especial en la morbimortalidad de los individuos, y los enfoques terapéuticos ante estas alteraciones, orientados a las características particulares de este grupo poblacional.

Palabras clave:
Envejecimiento
Riñón
HTA
Riesgo cardiovascular
ERC

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