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Vol. 158. Issue 1.
Pages 20-23 (January 2022)
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Vol. 158. Issue 1.
Pages 20-23 (January 2022)
Brief report
Clinical and microbiological characteristics of patients with Raoultella spp. isolation in Bogotá, Colombia
Características clínicas y microbiológicas de pacientes con aislamiento por Raoultella spp. en Bogotá, Colombia
Juan Camilo Mottaa,
Corresponding author
juan.motta@urosario.edu.co

Corresponding author.
, Enrique Ucrosb, Mariana Reyes Reyc, Paula Daniela Gómezc, Magda Sánchezd
a Especialización en Medicina Interna, Escuela de Medicina y Ciencias de la Salud, Universidad del Rosario, Bogotá, Colombia
b Servicio de Medicina Interna, Fundación Cardioinfantil, Bogotá, Colombia
c Escuela de Medicina y Ciencias de la Salud, Universidad del Rosario, Bogotá, Colombia
d Unidad Microbiología, Fundación Cardioinfantil, Bogotá, Colombia
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Tables (2)
Table 1. Raoultella spp. isolates, demographic and clinical characteristics.
Table 2. Antimicrobial resistance profile.
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Additional material (1)
Abstract
Introduction

Raoultella spp. is a gram-negative bacillus with increasing clinical importance due to the development of multi-drug resistance and because it has been reported as a cause of invasive infection. The risk of infection increases if comorbidities present such as diabetes mellitus and malignancies.

Methods

Descriptive study of clinical and microbiological characteristics in adult patients with Raoultella spp. isolation, treated at a fourth-level hospital in Bogotá, Colombia, between 2015 and 2020.

Results

61 patients with isolation of Raoultella spp., 51 were considered infection and 10 colonisation. The associated comorbidities were hypertension (n = 26, 42.6%), heart failure (n = 19, 31.1%) and diabetes mellitus (n = 18, 29.5%). AmpC resistance patterns were found in 10 samples (16.4%) and KPC in 3 (4.9%).

Conclusions

Raoultella spp. is of clinical importance due to its isolation in immunocompromised patients with multiple comorbidities and due to the increase in multi-resistant strains.

Keywords:
Raoultella ornithinolytica
Raoultella planticola
Infections
Humans
Drug resistance multiple
Resumen
Introducción

Raoultella spp. es un bacilo gramnegativo con importancia clínica creciente por el desarrollo de multirresistencia y porque se ha reportado como causal de infección invasiva. El riesgo de infección aumenta si se presentan comorbilidades como diabetes mellitus y neoplasias.

Métodos

Estudio descriptivo de las características clínicas y microbiológicas en pacientes adultos con aislamiento de Raoultella spp., atendidos en un hospital de cuarto nivel de Bogotá, Colombia, entre 2015 y 2020.

Resultados

Se identificaron 61 pacientes con aislamiento de Raoultella spp., 51 se consideraron infección y 10, colonización. Las comorbilidades asociadas fueron hipertensión arterial (n = 26, 42,6%), fallo cardiaco (n = 19, 31,1%) y diabetes mellitus (n = 18, 29,5%). Se encontraron patrones de resistencia AmpC en 10 muestras (16,4%) y KPC en 3 (4,9%).

Conclusiones

Es una infección emergente de importancia clínica por su aislamiento en pacientes inmunocomprometidos con múltiples comorbilidades y por el aumento de cepas multirresistentes.

Palabras clave:
Raoultella ornithinolytica
Raoultella planticola
Infecciones
Humanos
Resistencia microbiana a antibióticos

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