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Journal Information
Vol. 36. Issue 6.
Pages 363-369 (November - December 2021)
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Vol. 36. Issue 6.
Pages 363-369 (November - December 2021)
Original article
COVID-19 vaccination among Spanish nephrologists: Acceptance and side effects
Vacunación frente a la COVID-19 en nefrólogos: resultados de una encuesta nacional sobre aceptación y efectos adversos
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B. Quirogaa,e,
Corresponding author
borjaqg@gmail.com

Corresponding author.
, E. Sánchez-Álvarezb,e, M. Goicoecheac,e, P. de Sequerad,e, on behalf of the Spanish Society of Nephrology Council 1
a Nephrology Department, Hospital Universitario de La Princesa, Madrid, Spain
b Nephrology Department, Hospital Universitario de Cabueñes, Gijón, Spain
c Nephrology Department, Hospital Universitario Gregorio Marañón, Madrid, Spain
d Nephrology Department, Hospital Universitario Infanta Leonor, Madrid, Spain
e Spanish Society of Nephrology Council
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Tables (2)
Table 1. Covid-19 vaccine side effects in nephrologists.
Table 2. Side effects in nephrologists with the different vaccines (Pfizer-BioNTech® and Moderna®).
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Additional material (1)
Abstract
Introduction

Four vaccines against Covid-19 have been approved to date. Their acceptance and safety have not been addressed on healthcare workers. The aim of the present study is to evaluate vaccination rates and side effects among Spanish nephrologists.

Methods

All the Spanish nephrologists were invited to participate in this survey. Data on demographics, Covid-19 infection status, received vaccine doses and side effects were collected. Acceptance and side effects were analyzed for Covid-19 vaccination. Factors associated to vaccination were assessed and a multivariate adjusted model was constructed to determine independent predictors for Covid-19 vaccine side effects.

Results

A total of 708 nephrologists answered the survey (460 [65%] women, mean age 44±11 years). Six-hundred and eight (86%) had received the first dose and 513 (72%) were fully vaccinated. Most of the subjects (565, 93%) received BNT162b2 (Pfizer-BioNTech®) vaccine. Among vaccinated nephrologists, 453 (75%) presented any side effect; the most frequent was local reaction (68%), followed by myalgia (44%), tiredness (39%) and headache (34%). Age (OR 0.97, 95%CI [0.95–0.99], p<0.0001) and prior Covid-19 infection (OR 2.37, 95%CI [1.27–4.42], p=0.007) were independent predictors for developing side effects with Covid-19 vaccine. Overall side effects were similar with both vaccines, being myalgia (p=0.006) and tiredness (p=0.032) more frequent with the Pfizer-BioNTech® one.

Conclusion

Age and prior Covid-19 infection were predictors of vaccination side effects among Spanish nephrologists.

Keywords:
Covid-19 vaccine
Healthcare workers
Nephrologists
Side effects
Resumen
Introducción

Hasta la fecha, 4 vacunas han sido aprobadas frente a la Covid-19. Su aceptación y la presencia de efectos secundarios en personal sanitario no ha sido evaluado. El objetivo del presente estudio fue evaluar la tasa de vacunación entre los nefrólogos que ejercen su profesión en España, así como los efectos secundarios.

Métodos

Se invitó a todos los nefrólogos españoles a completar una encuesta online sobre los objetivos del estudio. Se recogieron datos demográficos, sobre la situación infecciosa del Covid-19, la vacuna recibida y la aparición de efectos secundarios. Se analizaron los factores asociados a la vacunación, así como las variables predictoras de reacciones adversas.

Resultados

Un total de 708 nefrólogos respondieron a la encuesta (460 [65%] mujeres, edad 44±11 años). Seiscientos ocho (86%) de los nefrólogos encuestados recibieron al menos una dosis de la vacuna y 513 (72%) la vacunación completa. La mayor parte de ellos (565; 93%) recibieron la vacuna BNT162b2 (Pfizer-BioNTech®). Entre los nefrólogos vacunados, 453 (75%) presentaron algún efecto secundario; el más frecuente fue la reacción local (68%), seguido de mialgias (44%), astenia (39%) y cefalea (34%). La edad (OR: 0,97; IC95% [0,95-0,99]; p<0,0001) y la infección previa por Covid-19 (OR: 2,37; IC95% [1,27-4,42]; p=0,007) fueron predictores independientes del desarrollo de síntomas tras la vacuna. En conjunto, los efectos secundarios fueron similares con ambas vacunas, siendo las mialgias (p=0,006) y la astenia (p=0,032) más frecuentes con la vacuna Pfizer-BioNTech®.

Conclusión

La edad y el antecedente de infección por Covid-19 fueron predictores de efectos secundarios con la vacuna entre los nefrólogos que ejercen en España y que contestaron la encuesta.

Palabras clave:
Vacunación Covid-19
Trabajador sanitario
Nefrólogos
Efectos secundarios

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