Buscar en
Gastroenterología y Hepatología (English Edition)
Toda la web
Inicio Gastroenterología y Hepatología (English Edition) Paterson-Brown-Kelly syndrome
Journal Information
Vol. 41. Issue 10.
Pages 650-651 (December 2018)
Share
Share
Download PDF
More article options
Vol. 41. Issue 10.
Pages 650-651 (December 2018)
Image of the month
Full text access
Paterson-Brown-Kelly syndrome
Síndrome de Paterson Brown Kelly
Visits
...
Satvinder Singh Bakshi1
Associate Professor of ENT, Department of ENT and Head & Neck Surgery, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Pillaiyarkuppam, Pondicherry, India
Article information
Full Text
Download PDF
Statistics
Figures (2)
Full Text
Medical image

A 21-year-old woman presented with gradually progressive dysphagia for 4 months. On examination she was pale and had glossitis, cheilitis and koilonychia. The Barium swallow revealed a 8mm web in the post cricoid region (Fig. 1) and blood smear showed microcytic hypochromic anemia with anisocytosis. Other values were Hemoglobin of 4g/dL (12–14), MCV 63fL (80–95), MCH 17pg/dL (27–32), Serum Iron 20μg/dL (50–140), Serum Ferritin 13ng/mL (25–250), and total iron binding capacity 480μg/dL (245–450). A provisional diagnosis of Paterson Brown Kelly syndrome was made and the patient was treated with dilatation of the web (Fig. 2). The anemia was corrected with 2 units of packed cell transfusion and oral hematinics and it improved to 10g/dL. Paterson Brown Kelly Syndrome or Sideropenic dysphagia consists of a triad of dysphagia, iron deficiency anemia and esophageal webs. The exact etiology is unknown although nutritional deficiencies and some genetic factors have been implicated. It is more common in females and patients usually present with progressive dysphagia along with symptoms of iron deficiency anemia like easy fatigability. The prognosis is good however since it is thought to be a premalignant condition and regular surveillance with annual endoscopy should be done.

Figure 1.

Barium swallow showing the post cricoid web.

(0.05MB).
Figure 2.

Endoscopic picture of the web.

(0.08MB).

Institution where the work was done – MGMCRI.

Copyright © 2018. Elsevier España, S.L.U.. All rights reserved
Article options
Tools
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos