Regístrese
Buscar en
Gastroenterología y Hepatología (English Edition)
Toda la web
Inicio Gastroenterología y Hepatología (English Edition) Faecal immunochemical tests for haemoglobin (FIT) in the assessment of patients ...
Journal Information
Vol. 42. Issue 4.
Pages 263-270 (April 2019)
Share
Share
Download PDF
More article options
ePub
Visits
0
Vol. 42. Issue 4.
Pages 263-270 (April 2019)
Review
DOI: 10.1016/j.gastre.2019.03.003
Faecal immunochemical tests for haemoglobin (FIT) in the assessment of patients with lower abdominal symptoms: current controversies
Pruebas inmunoquímicas fecales (PIF) para determinar la hemoglobina en la evaluación de pacientes con síntomas abdominales inferiores: controversias actuales
Visits
0
Callum G. Fraser
Centre for Research into Cancer Prevention and Screening, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland, UK
This item has received
0
Visits
Article information
Abstract
Full Text
Bibliography
Download PDF
Statistics
Tables (1)
Table 1. Advantages and disadvantages of qualitative and quantitative faecal immunochemical tests for haemoglobin (FIT).
Abstract

Faecal immunochemical tests for haemoglobin (FIT), as an adjunct to clinical information, assist in the triage of patients presenting in primary care with lower abdominal symptoms. Controversy remains regarding whether and which qualitative and quantitative FIT can be used, which groups of patients would benefit most from FIT, whether FIT should be done in primary and/or secondary care, and how FIT should be incorporated into diagnostic pathways. Controversy also exists as to the optimum cut-off used for referral for colonoscopy. A single sample of faeces may be sufficient. Reporting of results requires consideration. FIT provide a good rule in test for colorectal cancer and a good rule out test for significant bowel disease, but robust safety-netting is required for patients with negative results and ongoing symptoms. Risk scoring models have been developed, but their value is unclear as yet. Further evaluation of these topics is required to inform good practice.

Keywords:
Colorectal cancer
Faecal haemoglobin
Faecal immunochemical test
Faecal occult blood test
Lower abdominal symptoms
Significant bowel disease
Abbreviations:
AA
AN
ACRN
AUC
CRC
f-Hb
FIT
Hb
HGD
IBD
LoD
LoQ
POC
PPV
SBD
Resumen

Las pruebas inmunoquímicas fecales (PIF) para determinar la hemoglobina, como pruebas complementarias de la información clínica, ayudan a la selección de pacientes que acuden a Atención Primaria con síntomas abdominales inferiores. Sin embargo, continúa la polémica sobre si utilizar PIF y, en ese caso, si utilizar PIF cualitativas o cuantitativas, qué grupos de pacientes se beneficiarían más de las PIF, si las PIF deben realizarse en Atención Primaria o en el especialista, y cómo las PIF deben incorporarse a los protocolos de diagnóstico. También hay polémica sobre el valor de corte óptimo utilizado para la derivación a colonoscopia. Una sola muestra de heces puede ser suficiente. La notificación de los resultados exige análisis. Las PIF son un buen principio en la prueba del cáncer colorrectal y una buena prueba para descartar una enfermedad intestinal importante, pero se necesita una red de protección sólida para los pacientes con resultados negativos y síntomas continuos. Se han elaborado modelos de puntuación de riesgo, pero su valor aún no está claro. Se requiere una evaluación adicional de estos temas para lograr una buena práctica.

Palabras clave:
Cáncer colorrectal
Hemoglobina fecal
Prueba inmunoquímica fecal
Prueba de sangre oculta en materia fecal
Síntomas abdominales inferiores
Enfermedad intestinal importante

Article

These are the options to access the full texts of the publication Gastroenterología y Hepatología (English Edition)
Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe
Subscribe to

Gastroenterología y Hepatología (English Edition)

Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
E-mail
Article options
Tools
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos

es en pt
Política de cookies Cookies policy Política de cookies
Utilizamos cookies propias y de terceros para mejorar nuestros servicios y mostrarle publicidad relacionada con sus preferencias mediante el análisis de sus hábitos de navegación. Si continua navegando, consideramos que acepta su uso. Puede cambiar la configuración u obtener más información aquí. To improve our services and products, we use "cookies" (own or third parties authorized) to show advertising related to client preferences through the analyses of navigation customer behavior. Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here. Utilizamos cookies próprios e de terceiros para melhorar nossos serviços e mostrar publicidade relacionada às suas preferências, analisando seus hábitos de navegação. Se continuar a navegar, consideramos que aceita o seu uso. Você pode alterar a configuração ou obter mais informações aqui.