Methotrexate carried in lipid core nanoparticles reduces microglial activation and induces neuroprotection after cortical stroke induced in rats Edmundo L.R. Pereira; Raul C. Maranhão; Michelle N.C. Dias; Ijair R. dos Santos; Carolina Ramos dos Santos; Moisés Hamoy; Danielle Cristine A. Feio; Priscila O. Carvalho; Jaqueline M. Bazioli; Aleksandra T. Morikawa; Walace Gomes-Leal;