Regístrese
Buscar en
Cirugía Española (English Edition)
Toda la web
Inicio Cirugía Española (English Edition) Appendicular Deciduosis as a Cause of Acute Abdomen
Journal Information
Vol. 96. Issue 6.
Pages 383-384 (June - July 2018)
Vol. 96. Issue 6.
Pages 383-384 (June - July 2018)
Scientific letter
DOI: 10.1016/j.cireng.2018.06.002
Full text access
Appendicular Deciduosis as a Cause of Acute Abdomen
Deciduosis apendicular como causa de abdomen agudo
Visits
...
Alexis Luna Aufroya,
Corresponding author
aluna@tauli.cat

Corresponding author.
, Ruth Orellana Fernándezb, Mariona Novell Graub, Joan Carles Ferreres Piñasb, Salvador Navarro Sotoa
a Servicio de Cirugía General, Hospital Universitario Parc Taulí, Sabadell, Barcelona, Spain
b Servicio de Anatomía Patológica, Hospital Universitario Parc Taulí, Sabadell, Barcelona, Spain
Article information
Full Text
Bibliography
Download PDF
Statistics
Figures (1)
Tables (1)
Table 1. Internationally Published Cases of Deciduosis of the Appendix.
Full Text

Ectopic decidua or deciduosis is the presence of decidual cells outside the endometrium. This condition can affect the ovaries, uterine serosa, fallopian tubes or cervix. Less frequently, it can affect the appendix, diaphragm, liver, spleen, retroperitoneal lymphatic tissue or renal pelvis.1 The ectopic decidual cells located in the subceloma stroma may represent a physiological reaction secondary to the stimulation of progestogens.2 Usually, the condition is asymptomatic and regresses during the weeks after childbirth, but may reappear in later pregnancies. Occasionally, it may appear in the form of abdominal pain during pregnancy or as appendicitis in 0.05%–0.13% of cases.3–6 In the international literature, only 10 cases of deciduosis of the appendix during pregnancy have been described7–9 (Table 1), so we therefore present our case.

Table 1.

Internationally Published Cases of Deciduosis of the Appendix.

  Weeks of pregnancy  Diagnosis (clinical or radiological)  Pathology results  Evolution 
Garcia et al.3 (2001)  36  Clinical symptoms  Deciduosis of the appendix, acute appendicitis and bleeding  Resolution after surgery 
Bengoechea et al.5 (2015)  38  Clinical symptoms  Periappendiceal peritoneal deciduosis, acute apendicitis  Resolution after surgery 
Suster et al.4 (1990)  Case 1: 31
Case 2: 26
Case 3: 28
Case 5: 30 
Clinical symptoms  Deciduosis of the appendix, acute appendicitis  Resolution after surgery 
Gómez et al.8 (2004)  41  Incidental during cesarean section in the form of multiple peritoneal implants  Disseminated peritoneal deciduosis  Resolution after surgery 
Chai and Wijesuriya9
(2016) 
Case 1: 26
Case 2: 20
Case 3 and 4: not specified 
Case 1: clinical and radiological
Case 2: clinical and radiological
Case 3 and 4: clinical and radiological 
Case 1: periappendiceal peritoneal deciduosis
Case 2: subserous deciduosis
Case 3 and 4: deciduosis of the appendix 
Resolution after surgery 

The patient is a 32-year-old woman with a history of endometriosis. At 23 weeks of pregnancy, she came to the emergency room with acute abdomen that had been progressing over the previous 12h. Examination of the abdomen showed a palpable uterus in the umbilical area and pain predominantly in the right flank. Gynecological examination, ultrasound and amniocentesis detected no alterations. Blood work demonstrated leukocytosis. The appendix could not be visualized on ultrasound or MRI, although free fluid was observed between the bowel loops. Given the suspicion of acute appendicitis, exploratory laparoscopy was performed, which revealed suppurative appendicitis, and appendectomy was conducted. The pain subsided after the appendectomy, and the postoperative period was uneventful. The histological study observed solid nests of decidual cells in the appendicular wall, at the levels of the muscularis propria, subserosa and serosa, compatible with deciduosis of the appendix. Neutrophil polymorphonuclear leukocytes were not identified in the total inclusion of the surgical piece (Fig. 1).

Fig. 1.

Solid nests of decidual cells in the appendiceal wall at the level of the muscularis propria, subserosa and serosa, compatible with deciduosis of the appendix.

(0.18MB).

Deciduosis is an asymptomatic process associated with pregnancy, although in some cases it may present with symptoms of acute abdomen and should be included in the differential diagnosis as a possible cause in pregnant patients. The clinical presentation in the form of acute appendicitis could be attributed to peritoneal irritation due to mechanical factors associated with the response of the ectopic decidua to the estrogenic stimulus, or humoral factors since the decidua contains large concentrations of prostaglandins that act as a powerful muscle stimulant. Excessive secretion of microsomal acid phosphatase by decidual cells may increase the synthesis of prostaglandins, causing contraction of the appendix muscle wall.4 The case we present corresponds with appendicular deciduosis with acute abdominal symptoms during the second trimester of pregnancy whose symptoms completely subsided after appendectomy.

References
[1]
A. Balta, M. Lubgane, I. Orube, G. Ziemele, A. Vanags, J. Gardovskis, et al.
Deciduosis of the appendix manifesting as acute abdomen in pregnancy.
Acta Chir Latv, 14 (2014), pp. 43-45
[2]
J. Hauptmann, G. Mechtersheimer, H. Blaker, W. Schaupp, H.F. Otto.
Deciduosis of the appendix. Differential diagnosis of acute appendicitis.
Chirurg, 71 (2000), pp. 89-92
[3]
H. Garcia, M. Fodor, A. Giovannoni, L. Gidekel.
Deciduosis of the appendix as cause of acute abdomen in pregnancy.
Medicina (B Aires), 61 (2001), pp. 185-186
[4]
A. Bengoechea, I. Alarcón del Agua, D. Pérez, J.M. Pacheco, J.L. Fernández.
Deciduosis apendicular como forma de presentación de abdomen agudo.
Ginecol Obstet, 42 (2015), pp. 95-96
[5]
A. Buttner, R. Bassler, C. Theele.
Pregnancy associated ectopic deciduas (deciduosis) of the greater omentum: an analysis of 60 biopsies with cases of fibrosing deciduosis and leiomyomatosis peritonealis disseminata.
Pathol Res Pract, 189 (1993), pp. 352-359
[6]
P. Zaytsev, J.B. Taxy.
Pregnancy-associated ectopic decidua.
Am J Surg Pathol, 11 (1987), pp. 526-530
[7]
S. Suster, C.A. Moran.
Deciduosis of the appendix.
Am J Gastroenterol, 85 (1990), pp. 841-845
[8]
M.D. Gómez, M.D. Sánchez, E. Huelga.
Deciduosis peritoneal.
Prog Obstet Ginecol, 47 (2004), pp. 300-302
[9]
D. Chai, R. Wijesuriya.
Ann R Coll Surg Engl, 98 (2016), pp. e200-e202

Please cite this article as: Luna Aufroy A, Orellana Fernández R, Novell Grau M, Ferreres Piñas JC, Navarro Soto S. Deciduosis apendicular como causa de abdomen agudo. Cir Esp. 2018;96:383–384.

Copyright © 2017. AEC
Article options
Tools
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos

es en pt
Política de cookies Cookies policy Política de cookies
Utilizamos cookies propias y de terceros para mejorar nuestros servicios y mostrarle publicidad relacionada con sus preferencias mediante el análisis de sus hábitos de navegación. Si continua navegando, consideramos que acepta su uso. Puede cambiar la configuración u obtener más información aquí. To improve our services and products, we use "cookies" (own or third parties authorized) to show advertising related to client preferences through the analyses of navigation customer behavior. Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here. Utilizamos cookies próprios e de terceiros para melhorar nossos serviços e mostrar publicidade relacionada às suas preferências, analisando seus hábitos de navegação. Se continuar a navegar, consideramos que aceita o seu uso. Você pode alterar a configuração ou obter mais informações aqui.