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Archivos de la Sociedad Española de Oftalmología (English Edition) Reversible syphilitic ellipsoiditis
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Vol. 100. Issue 12.
Pages 812-813 (December 2025)
Ophthalmology in images
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Reversible syphilitic ellipsoiditis
Reversibilidad de la elipsoiditis sifilítica
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F. Garcia Ibor, N. Ruiz del Rio
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Noemi.Ruiz-Rio@uv.es

Corresponding author.
, A. Caro Ortega
Hospital Clínico Universitario de Valencia, Valencia, Spain
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The incidence of syphilis is increasing. Syphilitic uveitis may present clinically as an outer retinopathy with different patterns.1 On optical coherence tomography (OCT), its appearance resembles acute zonal outer retinopathy. The ellipsoid zone line disappears or is interrupted, and the external limiting membrane (ELM) line is attenuated. Some authors have referred to this as ellipsoiditis. Early diagnosis and treatment are essential. Recovery of the fine retinal structure and its function is very rapid. The OCT images correspond to presentation and to 1 and 4 weeks after initiation of penicillin therapy (Fig. 1).

Fig. 1
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None declared.

Ethical considerations

This study was conducted in full compliance with the ethical principles set forth in the Declaration of Helsinki. Written informed consent was obtained from the patient for possible publication of the clinical images.

Declaration on the use of artificial intelligence

Generative artificial intelligence was not used for writing, data analysis, or interpretation of results in this study.

Author’s contributions

All authors contributed substantially to the development of the study and manuscript, and they meet the authorship criteria established by the International Committee of Medical Journal Editors (ICMJE).

Conflicts of interest

None declared.

References
[1]
A. Vaze, R.E. De Angelis, M. Simões, T.E. Arantes, R. Moreto, G.F. Oliver, et al.
Optical coherence tomography findings in ocular syphilis involving the posterior segment of the eye.
Ocul Immunol Inflamm, 30 (2022), pp. 1464-1470
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