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DOI: 10.1016/j.oftale.2019.04.004
Available online 15 June 2019
Choroidal neovascular membrane associated with unilateral retinitis pigmentosa
Membrana neovascular coroidea asociada a retinitis pigmentosa unilateral
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M.J. Montoya Delgado
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manuel.montiya77@gmail.com

Corresponding author.
, G. Ríos Nequis, A. Ramírez Estudillo
Departamento de Retina y Vítreo, Fundación Hospital Nuestra Señora de la Luz, Mexico City, Mexico
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Received 20 March 2019. Accepted 13 April 2019
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Abstract

A 67 year-old woman with diabetes mellitus type 2 no medical background of interest was attended in hospital due to visual loss of left eye of 4 months of onset. The fundus examination revealed findings corresponding to moderate non-proliferative diabetic retinopathy in the right eye and pigmented lesions similar to bone spicules and atrophy of the retinal pigment epithelium in the middle periphery and in the macular area in the left eye. The full-field electroretinogram was flat, with a slight insinuation of the b-wave in the light adaptation with a single flash of 3.0cd in the left eye. The optical coherence tomography showed the atrophic retina in all its layers, as well as intraretinal cysts and a serous neurosensory detachment of the macular retina with a lesion of high reflectivity in the left eye. Infectious and inflammatory diseases were ruled out. Three doses of intravitreal ranibizumab were administered monthly.

The presence of choroidal neovascular membrane associated with unilateral retinitis pigmentosa has not been previously reported. The patient improved with intravitreal ranibizumab.

Keywords:
Choroidal neovascular membrane
Unilateral retinitis pigmentosa
Intravitreal ranibizumab
Resumen

Mujer de 67 años con diabetes mellitus tipo 2 sin otros antecedentes de interés que consultó por disminución de agudeza visual de su ojo izquierdo de 4 meses de evolución. El examen de fondo de ojo reveló datos de retinopatía diabética no proliferativa moderada en el ojo derecho y lesiones pigmentadas en forma de espículas óseas y atrofia del epitelio pigmentario retiniano en la media periferia y en el área macular en el ojo izquierdo. El electrorretinograma de campo completo se mostró plano, con una insinuación leve de la onda b en adaptación a la luz con destello único de 3,0cd en el ojo izquierdo. En la tomografía de coherencia óptica se vio la retina atrófica en todas sus capas, quistes intrarretinianos y un desprendimiento neurosensorial seroso de la retina macular con una lesión subretiniana de alta reflectividad en el ojo izquierdo. Fueron descartadas causas infecciosas e inflamatorias. Se administraron 3 inyecciones de ranibizumab intravítreo con periodicidad mensual.

La presencia de membrana neovascular coroidea asociada con retinitis pigmentosa unilateral no ha sido publicada previamente. El presente caso respondió a ranibizumab intravítreo.

Palabras clave:
Membrana neovascular coroidea
Retinitis pigmentosa unilateral
Ranibizumab intravítreo

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