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Archivos de la Sociedad Española de Oftalmología (English Edition) Retained Descemet's membrane after penetrating keratoplasty with previous D...
Journal Information
Vol. 100. Issue 12.
Pages 802-807 (December 2025)
Vol. 100. Issue 12.
Pages 802-807 (December 2025)
Clinical Case
Retained Descemet's membrane after penetrating keratoplasty with previous Descemet's membrane endothelial keratoplasty
Membrana de Descemet retenida tras queratoplastia penetrante con queratoplastia endotelial de la membrana de Descemet previa
L. Domínguez Garcíaa,
Corresponding author
Laudominguez97@gmail.com

Corresponding author.
, P. Vázquez Colomoa, P. Spang-Valenciaa, S. Quiñones Garridob, E. Ruiz Bravo-Burguillosb
a Servicio de Oftalmología, Hospital Universitario La Paz, Madrid, Spain
b Servicio de Anatomía Patológica, Hospital Universitario La Paz, Madrid, Spain
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Abstract

Although keratoplasties are key surgical procedures for treating corneal diseases, they may present late complications such as retrocorneal membranes. We present an unusual case following a penetrating keratoplasty (PKP) in a patient with a history of DMEK. This is the case of an 85-year-old woman with a past medical history of DMEK and 2 PKPs due to previous graft failures, who developed a retrocorneal membrane 6 months after the last PKP. A membranectomy was performed. Histological analysis confirmed the presence of retained Descemet’s membrane and decreased endothelial cell density. Visual acuity remained stable (0.4–0.63) with no signs of edema. No recurrence was observed. Late retention of Descemet’s membrane may result from incomplete descemetorhexis, among other causes. Although asymptomatic, it may require surgery. Close postoperative follow-up is essential.

Keywords:
Retrocorneal membrane
Descemet
Penetrating keratoplasty
Resumen

Las queratoplastias son cirugías clave para tratar enfermedades corneales, aunque pueden presentar complicaciones tardías como membranas retrocorneales. Se expone un caso inusual tras una queratoplastia penetrante (QPP) en una paciente con antecedente de DMEK.Describimos el caso de una mujer de 85 años con antecedentes de DMEK y dos QPP por fracasos previos, que desarrolló una membrana retrocorneal seis meses después de la última QPP. Se realizó membranectomía. El estudio histológico confirmó la presencia de membrana de Descemet retenida y disminución de células endoteliales. La agudeza visual se mantuvo estable (0,4–0,63) sin edema. No hubo recidiva. La retención tardía de membrana de Descemet puede deberse a descematorrexis incompleta entre otras causas. Aunque asintomática, puede requerir cirugía. Es clave el seguimiento postoperatorio.

Palabras clave:
Membrana retrocorneal
Descemet
Queratoplastia penetrante

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