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Vol. 92. Issue 9.
Pages 447-450 (September 2017)
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Vol. 92. Issue 9.
Pages 447-450 (September 2017)
Short communication
Neurotrophic keratopathy in a patient with familial amyloidosis
Queratopatía neurotrófica corneal bilateral en paciente con amiloidosis familiar bilateral
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A.M. de Carvalho Mendes Castenheira
Corresponding author
amelia_cast@hotmail.com

Corresponding author.
, P. Pujol Vives, M. Asaad Ammaar
Consorci Sanitari de Terrassa, Tarrasa (Barcelona), Spain
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Abstract
Introduction

Familial amyloidotic polyneuropathy is a disease related to amyloid material deposits in the extracellular matrix that can affect many tissues, including the eye.

Case report

This case includes clinical data, a full corneal study report, and histopathological findings, as well as the treatment and follow up of bilateral neurotrophic keratopathy in a 33 year-old patient with familial amyloidotic polyneuropathy.

Discussion

Although amyloidotic deposits were also found in the conjunctival tissue, this is not a typical form of ophthalmic amyloidosis. The corneal wound in this case is a result of a corneal anesthesia due to the systemic polyneuropathy.

Keywords:
Familial amyloidosis
Polyneuropathy
Neurotrophic keratopathy
Resumen
Introducción

La amiloidosis familiar es una enfermedad caracterizada por el depósito extracelular de un material denominado amiloide que puede afectar a gran variedad de órganos, incluyendo el ojo.

Caso clínico

Se presentan datos clínicos, pruebas complementarias e histológicas, así como el tratamiento y seguimiento de un paciente de 33 años con úlcera neurotrófica corneal bilateral, debida a una polineuropatía amiloidótica familiar.

Discusión

Este caso no es la forma típica de presentación de la amiloidosis oftálmica, ya que la úlcera corneal es el resultado de la anestesia causada por la polineuropatía sistémica, aunque se encontraron depósitos de amiloide en el tejido conjuntival.

Palabras clave:
Amiloidosis familiar
Polineuropatía
Queratopatía neurotrófica

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