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Inicio Archivos de la Sociedad Española de Oftalmología (English Edition) Interferon alpha-2a as alternative treatment for conjunctival squamous cell carc...
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Vol. 92. Issue 11.
Pages 539-542 (November 2017)
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Vol. 92. Issue 11.
Pages 539-542 (November 2017)
Short communication
Interferon alpha-2a as alternative treatment for conjunctival squamous cell carcinoma
Interferón alfa-2a como tratamiento alternativo para el carcinoma conjuntival de células escamosas
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D. Cruzado-Sáncheza,
Corresponding author
dcruzados@gmail.com

Corresponding author.
, M. Salas-Diazb, W.A. Tellezc, S.E. Alvarez-Matosc, S. Serpa-Fríasa
a Servicio de Oftalmología Oncológica, Departamento de Cabeza y Cuello, Instituto Nacional de Enfermedades Neoplásicas (INEN), Peru
b Universidad Nacional Federico Villarreal, Peru
c Sociedad Científica de Estudiantes de Medicina Villarrealinos (SOCEMVI), Universidad Nacional Federico Villarreal (UNFV), Peru
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Abstract
Case report

A 35 year-old male patient with a history of HIV infection characterized by progressive tumor growth in bulbar conjunctiva of the left eye, corresponding to conjunctival squamous cell carcinoma that responded to treatment with interferon alpha-2a.

Discussion

Interferon alpha-2b has been used at conjunctival level as a topical immunomodulator treatment, with complete remission of epithelial neoplasms being observed. However, there have not been any previous publications on the use of interferon alpha-2a, which differs from interferon alpha-2b in a single amino acid, for the treatment of conjunctival squamous cell carcinoma.

Keywords:
Interferon alpha-2a
Conjunctival squamous cell carcinoma
Conjunctiva
Resumen
Caso clínico

Paciente varón de 35 años con antecedente de infección por VIH, caracterizado por tumoración de crecimiento progresivo en conjuntiva bulbar de ojo izquierdo correspondiente a un carcinoma conjuntival de células escamosas que responde a tratamiento con interferón alfa-2a.

Discusión

A nivel conjuntival, el interferón alfa-2b tópico ha sido utilizado como tratamiento inmunomodulador, con el que se observó remisión completa de las neoplasias epiteliales; sin embargo, no se ha publicado el uso del interferón alfa-2a para el tratamiento de carcinoma conjuntival de células escamosas, el cual difiere del intererón alfa-2b en un solo aminoácido.

Palabras clave:
Interferón alfa-2a
Carcinoma conjuntival de células escamosas
Conjuntiva

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