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Inicio Archivos de la Sociedad Española de Oftalmología (English Edition) Effectiveness of topical bevacizumab in bilateral primary lipid keratopathy
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Vol. 86. Issue 11.
Pages 374-376 (November 2011)
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Vol. 86. Issue 11.
Pages 374-376 (November 2011)
Short communication
Effectiveness of topical bevacizumab in bilateral primary lipid keratopathy
Eficacia de bevacizumab tópico en queratopatía lipoidea bilateral primaria
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1199
M. Castro-Rebollo
Corresponding author
cinta.perezrico@gmail.com

Corresponding author.
, M.A. Montes-Mollón, C. Pérez-Rico, M.A. Teus
Servicio de Oftalmología, Hospital Universitario Príncipe de Asturias, Universidad de Alcalá, Alcalá de Henares, Madrid, Spain
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Abstract
Case report

A 75-year-old man with bilateral idiopathic lipid keratopathy underwent a penetrating keratoplasty in the left eye. One month later, there was deep corneal neovascularisation extending across the bed and the graft–host interface, with a whitish opacity surrounding the vessels. Topical bevacizumab (25mg/mL) was administered 4 times daily for 2 months with partial regression of corneal neovascularization.

Discussion

Topical bevacizumab may be useful in preventing a recurrence of lipid deposition after penetrating keratoplasty in patients with bilateral primary lipid keratopathy, although its long-term efficacy needs to be assessed.

Keywords:
Bilateral primary lipid keratopathy
Topical bevacizumab
Corneal neovascularisation
Resumen
Caso clínico

Varón de 75 años con queratopatía lipoidea bilateral primaria. Es intervenido de queratoplastia penetrante en ojo izquierdo. Al mes se observa neovascularización corneal profunda extendiéndose sobre el lecho y la interfase injerto-huésped, con opacidad blanquecina alrededor de los neovasos. Se inicia tratamiento con bevacizumab tópico (25mg/mL) 4 veces/día durante 2 meses, con regresión parcial de la neovascularización corneal.

Discusión

Bevacizumab tópico puede ser útil en la prevención de la recidiva de la queratopatía lipoidea tras queratoplastia penetrante en pacientes con queratopatía lipoidea bilateral primaria, aunque sería conveniente determinar su eficacia a largo plazo.

Palabras clave:
Queratopatía lipoidea bilateral primaria
Bevacizumab tópico
Neovascularización corneal

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