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Inicio Archivos de la Sociedad Española de Oftalmología (English Edition) Conjunctival myeloid sarcoma in acute myeloblastic leukemia-M1
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Vol. 87. Issue 3.
Pages 79-81 (March 2012)
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Vol. 87. Issue 3.
Pages 79-81 (March 2012)
Short communication
Conjunctival myeloid sarcoma in acute myeloblastic leukemia-M1
Sarcoma granulocítico conjuntival en leucemia mieloblástica aguda M1
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P. Méndez-Cepedaa,
Corresponding author
, A.C. Millán-Rodrígueza, E. Diosa, C. Alvarezb, C. Sevillanoa
a Servicio de Oftalmología, Complexo Hospitalario de Pontevedra, Pontevedra, Spain
b Servicio de Anatomía Patológica, Complexo Hospitalario de Pontevedra, Pontevedra, Spain
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Abstract
Clinical case

A 69-year-old man with a history of acute myeloblastic leukemia-M1 presented with bilateral conjunctival injection. Ophthalmological examination revealed lesions located at the upper tarsal conjunctiva of the right eye and lower tarsal conjunctiva of both eyes. Histological and immunohistochemical studies confirmed conjunctival myeloid sarcoma (MS). The patient died due to multiorgan failure three months later.

Discussion

Extramedullary recurrence of leukemia can appear as an ocular manifestation that brings about a recurrence of the leukemia, leading to a poor prognosis.

Keywords:
Acute myeloblastic leukemia
Myeloid sarcoma
Conjunctiva
Immunohistochemistry
Prognosis
Resumen
Caso clínico

Varón de 69 años diagnosticado de leucemia mieloblástica aguda M1 en remisión completa, remitido a Oftalmología por cuadro de ojo rojo no doloroso. Biomicroscópicamente se observan lesiones sobreelevadas asalmonadas en conjuntiva tarsal superior de ojo derecho e inferior de ambos ojos. Mediante estudios histológicos e inmunohistoquímicos se confirma recidiva extramedular en forma de sarcoma mieloide en conjuntiva. El paciente fallece a los 3 meses de un fallo multiorgánico.

Discusión

La recidiva extramedular de una leucemia puede presentarse como una manifestación ocular que conlleva una recurrencia de la leucemia, siendo esta de mal pronóstico.

Palabras clave:
Leucemia mieloblástica aguda
Sarcoma granulocítico
Conjuntiva
Inmunohistoquímica
Pronóstico

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